Semaphorins deployed to repel cell migrants at spinal cord borders.

Semaphorins deployed to repel cell migrants at spinal cord borders.
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DOI:
10.1186/jbiol65
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发表时间:
2008-01-01
期刊:
影响因子:
--
通讯作者:
Rougon, Genevieve
Rougon, Genevieve
中科院分区:
其他
文献类型:
--
作者:
Chauvet, Sophie;Rougon, Genevieve

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在脊髓中,发育中的运动神经元轴突向外周延伸,而其细胞体则留在脊髓的运动柱内。最近的两篇论文表明,这种分配涉及运动神经元和神经嵴边界帽细胞之间的正向和反向信号通路。
In the spinal cord, developing motor neurons extend their axons into the periphery while their cell bodies remain within the motor columns in the spinal cord. Two recent papers show that this partitioning involves forward and reverse semaphorin-plexin signaling between motor neurons and neural crest boundary cap cells.