Numerical studies of blood shear and washing in a continuous flow ventricular assist device
Numerical studies of blood shear and washing in a continuous flow ventricular assist device
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DOI：
10.1097/00002480-200007000-00024
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发表时间：
2000-07-01
期刊：
影响因子：
4.2
通讯作者：
Bearnson, G
中科院分区：
文献类型：
--
作者：
Anderson, JB;Wood, HG;Bearnson, G
持续流动心室辅助装置（CF3）的第三个原型正在开发和测试中，用于人体植入。泵中的血液流过完全封闭的四叶叶轮（由磁力轴承支撑），并流过叶轮两侧的小间隙区域。计算流体动力学（CFD）的解决方案，这种流动已经获得了使用TascFlow，可从AEA技术，英国的软件包。这些流动解决方案已用于估计泵中血液上的剪应力，从而最大限度地减少溶血。此外，这些解决方案对于实现将提供良好的血液洗涤以最小化可能导致血栓形成的停滞点的可能性的设计是有益的。本研究对CF3中的这些现象进行了数值研究。计算出的剪切速率结果与公开文献中发表的值进行了比较。比较表明，溶血将不会是一个问题与CF3，这是在协议与初步的实验测量。正在进行流动研究，以确定清除区的最佳大小。
The third prototype of a continuous flow ventricular assist device (CF3) is being developed and tested for implantation in humans. The blood in the pump flows through a fully shrouded four bladed impeller (supported by magnetic bearings) and through small clearance regions on either side of the impeller. Computational fluid dynamics (CFD) solutions for this flow have been obtained by using TascFlow, a software package available from AEA Technology, UK. These flow solutions have been used to estimate the shear stresses on the blood in the pump and, hence, to minimize hemolysis. In addition, the solutions are informative for achieving a design that will provide good washing of the blood to minimize the possibility of stagnation points that can lead to thrombosis. This study presents numerical studies of these phenomena in the CF3. The calculated shear rate results are compared with values published in the open literature. The comparisons indicate that hemolysis will not be a problem with CF3, which is in agreement with preliminary experimental measurements. Flow studies are being conducted to determine the optimal size of the clearance regions.