Membrane dynamics of a myelin-like giant multilamellar vesicle applicable to a self-reproducing system
Membrane dynamics of a myelin-like giant multilamellar vesicle applicable to a self-reproducing system
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DOI：
10.1021/la049738a
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发表时间：
2004-05-11
期刊：
影响因子：
3.9
通讯作者：
Sugawara, T
中科院分区：
文献类型：
--
作者：
Takakura, K;Sugawara, T
真实的实时观察髓鞘样巨多层囊泡（MGW）揭示，当加入电解质的水溶液时，其分裂成相对小的mGMV。此外，当加入由电解质单元和囊泡两亲单元组成的bola两亲分子时，mGMV表现出伴随分裂mGMV生长的分裂过程。这种囊泡系统可以被认为是mGMV的自我复制，其中添加的两亲物充当囊泡两亲物和分裂引发剂两者的供应者。
real time observation of a myelin-like giant multilamellar vesicle (MGW) revealed that it divided into relatively small mGMVs when an aqueous solution of an electrolyte was added. Furthermore, the mGMV showed a division process accompanied by the growth of the dividing mGMVs when a bolaamphiphile which was composed of an electrolyte unit and a vesicular amphiphile unit was added. This vesicular system can be regarded as a self-reproduction of mGMV, where the added amphiphile acts as a supplier of both the vesicular amphiphile and the division initiator.