Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies.
Effect of Body Mass Index on pregnancy outcomes in nulliparous women delivering singleton babies.
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DOI：
10.1186/1471-2458-7-168
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发表时间：
2007-07-24
影响因子：
4.5
通讯作者：
Bhattacharya S
中科院分区：
文献类型：
--
作者：
Bhattacharya S;Campbell DM;Liston WA;Bhattacharya S
年轻妇女肥胖症的日益流行是一个主要的公共卫生问题。这些趋势对这些妇女的妊娠结局有重大影响，几位研究人员已经记录了这一点。在一项基于人群的队列研究中，使用常规收集的数据，本文探讨了增加体重指数（BMI）对分娩单胎婴儿的未经产妇女妊娠结局的影响。这是一项回顾性队列研究，基于1976年至2005年在阿伯丁分娩单胎婴儿的所有未经产妇女。妇女被分为五组-体重不足（BMI < 20 Kg/m2）、正常（BMI 20 - 24.9 Kg/m2）、超重（BMI 25 - 29.9 Kg/m2）、肥胖（BMI 30 - 34.9 Kg/m2）和病态肥胖（BMI > 35 Kg/m2）。通过单因素和多因素分析比较产科和围产期结局。与BMI 20 - 24.9的女性相比，病态肥胖女性面临先兆子痫的风险最高{OR 7.2（95% CI 4.7，11.2）}，体重过轻的女性最低{OR 0.6（95% CI 0.5，0.7）}。引产在病态肥胖妇女中最高{OR 1.8（95% CI 1.3，2.5）}，在体重不足妇女中最低{OR 0.8（95% CI 0.8，0.9）}。紧急剖腹产率在病态肥胖中最高{OR 2.8（95%CI 2.0，3.9）}，在正常和低BMI的女性中相当。肥胖女性更可能发生产后出血{OR 1.5（95% CI 1.3，1.7）}和早产（< 33周）{OR 2.0（95% CI 1.3，2.9）}。体重不足2,500 g的女性更常见{OR 1.7（95% OR 1.2，2.0）}。出生体重> 4，000 g的风险最高的是病态肥胖者{OR 2.1（95% CI 1.3，3.2）}，最低的是体重不足的妇女{OR 0.5（95% CI 0.4，0.6）}。体重指数增加与先兆子痫、妊娠期高血压、巨大儿、引产和剖腹产的发生率增加有关;而体重不足的妇女比体重指数正常的妇女有更好的妊娠结局。
The increasing prevalence of obesity in young women is a major public health concern. These trends have a major impact on pregnancy outcomes in these women, which have been documented by several researchers. In a population based cohort study, using routinely collected data, this paper examines the effect of increasing Body Mass Index (BMI) on pregnancy outcomes in nulliparous women delivering singleton babies. This was a retrospective cohort study, based on all nulliparous women delivering singleton babies in Aberdeen between 1976 and 2005. Women were categorized into five groups – underweight (BMI < 20 Kg/m2), normal (BMI 20 – 24.9 Kg/m2) overweight (BMI 25 – 29.9 Kg/m2), obese (BMI 30 – 34.9 Kg/m2) and morbidly obese (BMI > 35 Kg/m2). Obstetric and perinatal outcomes were compared by univariate and multivariate analyses. In comparison with women of BMI 20 – 24.9, morbidly obese women faced the highest risk of pre-eclampsia {OR 7.2 (95% CI 4.7, 11.2)} and underweight women the lowest {OR 0.6 (95% CI 0.5, 0.7)}. Induced labour was highest in the morbidly obese {OR 1.8 (95% CI 1.3, 2.5)} and lowest in underweight women {OR 0.8 (95% CI 0.8, 0.9)}. Emergency Caesarean section rates were highest in the morbidly obese {OR 2.8 (95% CI 2.0, 3.9)}, and comparable in women with normal and low BMI. Obese women were more likely to have postpartum haemorrhage {OR 1.5 (95% CI 1.3, 1.7)} and preterm delivery (< 33 weeks) {OR 2.0 (95% CI 1.3, 2.9)}. Birthweights less than 2,500 g were more common in underweight women {OR 1.7 (95% OR 1.2, 2.0)}. The highest risk of birth weights > 4,000 g was in the morbidly obese {OR 2.1 (95% CI 1.3, 3.2)} and the lowest in underweight women {OR 0.5 (95% CI 0.4, 0.6)}. Increasing BMI is associated with increased incidence of pre-eclampsia, gestational hypertension, macrosomia, induction of labour and caesarean delivery; while underweight women had better pregnancy outcomes than women with normal BMI.
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影响因子：
2.6
作者：
Abenhaim, Haim A.;Kinch, Robert A.;Usher, Robert
通讯作者：
Usher, Robert
影响因子：
7.2
作者：
Bianco, AT;Smilen, TW;Lockwood, CJ
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DOI：
10.1016/s0002-9378(85)80029-6
发表时间：
1985-01-01
影响因子：
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作者：
GARBACIAK, JA;RICHTER, M;BARTON, JJ
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DOI：
10.1016/0002-9378(95)90598-7
发表时间：
1995-02-01
影响因子：
9.8
作者：
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通讯作者：
YIP, R
影响因子：
4.3
作者：
Spinillo, A;Capuzzo, E;Di Mario, M
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Di Mario, M