Effects of personality traits on the manifestations of irritable bowel syndrome.
Effects of personality traits on the manifestations of irritable bowel syndrome.
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人格特征对肠易激综合征表现的影响。
DOI：
10.1186/1751-0759-6-20
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发表时间：
2012-10-30
影响因子：
2.1
通讯作者：
Fukudo S
中科院分区：
文献类型：
--
作者：
Tayama J;Nakaya N;Hamaguchi T;Tomiie T;Shinozaki M;Saigo T;Shirabe S;Fukudo S
此前的研究报告称，肠易激综合征(IBS)患者表现出高度的神经质。然而，在年轻人群中，IBS亚型和神经质程度之间的确切联系在很大程度上是未知的。我们测试了我们的假设，即以腹泻为主的IBS患者可能比没有IBS或其他IBS亚型的患者有更高程度的神经质。我们还验证了额外的假设，即神经质的严重程度可能与年轻人群中IBS的严重程度相关。我们对557名18-21岁的大学生进行了横断面调查。IBS的存在与否和IBS亚型的确定由罗马II模块化问卷确定，而IBS的严重程度则由IBS严重指数(IBS-SI)确定。用Maudly个性问卷(MPI)评定神经质的程度。用K6量表测量有无心理困扰。腹泻型IBS患者的神经质评分显著高于非IBS患者或便秘型IBS患者。所有IBS患者的神经质得分与IBS-SI得分显著相关。这些结果表明神经质参与了年轻受试者的IBS的病理生理学，特别是在以腹泻为主的亚型中。
Previous studies have reported that patients with irritable bowel syndrome (IBS) show high neuroticism. However, the precise association between the IBS subtypes and the degree of neuroticism in younger populations is largely unknown. We tested our hypothesis that subjects with diarrhea-predominant IBS may have a higher degree of neuroticism than subjects without IBS or those with other subtypes of IBS. We also verified the additional hypothesis that the severity of neuroticism might be correlated with the severity of IBS in younger populations. We conducted a cross-sectional survey of 557 university students, ranging in age from 18 to 21 years. Presence/ absence of IBS and determination of the IBS subtype was by the Rome II Modular Questionnaire, while the severity of IBS was determined by the IBS severity index (IBS-SI). The degree of neuroticism was evaluated using the Maudsely Personality Inventory (MPI). The presence/absence of psychological distress was measured with the K6 scale. Neuroticism scores in the subjects with diarrhea-predominant IBS were significantly higher than those in the non-IBS subjects or subjects with constipation-predominant IBS. The neuroticism scores were significantly correlated with the IBS-SI scores in all subjects with IBS. These results suggest that neuroticism is involved in the pathophysiology of IBS in young subjects, especially in that of the diarrhea-predominant subtype.