Methamphetamine and other substance use during pregnancy: Preliminary estimates from the infant development, environment, and lifestyle (IDEAL) study
Methamphetamine and other substance use during pregnancy: Preliminary estimates from the infant development, environment, and lifestyle (IDEAL) study
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DOI：
10.1007/s10995-005-0052-0
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发表时间：
2006-05-01
影响因子：
2.3
通讯作者：
Lester, Barry
中科院分区：
文献类型：
--
作者：
Arria, Amelia M.;Derauf, Chris;Lester, Barry
目的：在美国的几个地区，甲基苯丙胺的使用是一个持续存在的问题，但很少有研究关注产前甲基苯丙胺暴露。本研究的目的是估计的患病率和相关的酒精，烟草和其他物质的使用，包括甲基苯丙胺-在pregnancy.Methods：该样本包括第一个1632名合格的母亲同意参加一个大规模的多地点研究，重点是产前甲基苯丙胺暴露。这一筛查样本包括酒精、烟草、甲基苯丙胺和其他药物的使用者和非使用者。物质的使用是由产妇自我报告和/或GC/MS确认的阳性胎粪screen.Results：总体而言，5.2%的妇女使用甲基苯丙胺在怀孕期间的某个时候。四分之一的样本吸烟，22.8%饮酒，6.0%使用大麻，1.3%产前使用巴比妥类药物。不到1%的样本使用海洛因，苯二氮卓类和致幻剂。多变量建模结果表明，吸烟者和非法药物使用者更有可能是单一的，受教育程度较低，参加了不到11产前检查，并利用公共财政assistance.Conclusions：这是第一次大规模的调查报告的流行率在美国的甲基苯丙胺是一个值得关注的地区在怀孕期间使用甲基苯丙胺。正在进行后续研究，以调查与产前甲基苯丙胺接触有关的结果。鉴于这项研究扩展并证实了先前的研究结果，即可以根据基本的人口特征确定孕妇的高危群体，因此非常需要采取有针对性的干预措施，以减少与产前饮酒和吸烟有关的严重不良后果。
Objectives: Methamphetamine use is a continuing problem in several regions of the United States and yet few studies have focused on prenatal methamphetamine exposure. The purpose of this study was to estimate the prevalence and correlates of alcohol, tobacco, and other substance use-including methamphetamine-during pregnancy.Methods: The sample consisted of the first 1632 eligible mothers who consented to participate in a large-scale multisite study focused on prenatal methamphetamine exposure. This unselected screening sample included both users and nonusers of alcohol, tobacco, methamphetamine, and other drugs. Substance use was determined by maternal self-report and/or GC/MS confirmation of a positive meconium screen.Results: Overall, 5.2% of women used methamphetamine at some point during their pregnancy. One quarter of the sample smoked tobacco, 22.8% drank alcohol, 6.0% used marijuana, and 1.3% used barbiturates prenatally. Less than 1% of the sample used heroin, benzodiazapenes, and hallucinogens. Multivariate modeling results showed that tobacco smokers and illicit drug users were more likely to be single and less educated, have attended less than 11 prenatal visits, and utilize public financial assistance.Conclusions: This is the first large-scale investigation to report the prevalence of methamphetamine use during pregnancy in areas of the United States where methamphetamine is a notable concern. Follow-up research is ongoing to investigate the outcomes associated with prenatal methamphetamine exposure. Given that this research extends and confirms previous findings showing that high-risk groups of pregnant women can be identified on the basis of basic demographic characteristics, targeted interventions are greatly needed to reduce serious adverse outcomes associated with prenatal alcohol and tobacco use.