A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: Known and novel
A perspective on regulation of cell-cell adhesion and epithelial-mesenchymal transition: Known and novel
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DOI：
10.1159/000084512
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发表时间：
2005-01-01
影响因子：
2.7
通讯作者：
Wadham, C
中科院分区：
文献类型：
--
作者：
Khew-Goodall, Y;Wadham, C
该领域的一些最近的评论已经描述了许多已知的生长因子和信号通路，可能参与调节上皮-间充质转化。这一观点将集中在一些方面的翻译后调节细胞-细胞粘附，是不太好理解的，他们在启动上皮间质转化的潜在作用。此外，还将描述上皮-间充质转化信号通路中的潜在新型中间体。版权所有（C）2005 S. Karger AG，巴塞尔。
A number of recent reviews in the field have described many of the known growth factors and signalling pathways that may be involved in regulating epithelial-mesenchymal transitions. This perspective will focus on some aspects of posttranslational regulation of cell-cell adhesion that are less well understood and their potential role in initiating epithelial-mesenchymal transitions. In addition, a potential novel intermediate in the signalling pathway of epithelial-mesenchymal transition will also be described. Copyright (C) 2005 S. Karger AG, Basel.