Toxoplasma gondii: 25 years and 25 major advances for the field.
Toxoplasma gondii: 25 years and 25 major advances for the field.
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DOI：
10.1016/j.ijpara.2009.02.003
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发表时间：
2009-07-01
影响因子：
4
通讯作者：
Boothroyd JC
中科院分区：
文献类型：
--
作者：
Boothroyd JC
本文试图找出过去25年来弓形虫研究的最重要亮点。这是一个巨大进步的时期，并描述了作者认为最重要的25个进步。这些从长凳到床边，代表了无数调查人员的大量工作。而且，在阐述了如此多的发现之后，我们不可能不反思未来的挑战。这些，也简要讨论。最后，虽然已经尽一切努力将该领域视为一个整体，但作者的分子生物学背景几乎肯定会扭曲过去和未来进展的相对重要性。尽管如此，希望读者会同意，或者至少不会太强烈地反对，这里提出的大多数选择。
This article is an attempt to identify the most significant highlights of Toxoplasma research over the last 25 years. It has been a period of enormous progress and the top 25 most significant advances, in the view of this author, are described. These range from the bench to the bedside and represent a tremendous body of work from countless investigators. And, having laid out so much that has been discovered, it is impossible not to also reflect on the challenges that lie ahead. These, too, are briefly discussed. Finally, while every effort has been made to view the field as a whole, the molecular biology background of the author almost certainly will have skewed the relative importance attached to past and future advances. Despite this, it is hoped that the reader will agree with, or at least not disagree too strongly with, most of the choices presented here.
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