Longitudinal prevalence of major eye diseases
Longitudinal prevalence of major eye diseases
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DOI：
10.1001/archopht.121.9.1303
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发表时间：
2003-09-01
影响因子：
--
通讯作者：
Sloan, FA
中科院分区：
文献类型：
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作者：
Lee, PP;Feldman, ZW;Sloan, FA
目的：描述一组老年受试者中3种慢性眼病的患病率。研究设计：对医疗保险索赔的纵向观察。人群：随机抽取65岁及以上的医疗保险受益人，基线时具有全国代表性。主要结果测量：糖尿病视网膜病变、青光眼和年龄相关性黄斑变性的诊断。方法：受益人从1991年至1999年，除非死亡率或登记在一个健康维护组织6个月或以上的一年干预。对索赔数据进行了分析，以确定是否存在国际疾病分类第九版临床修订版中的代码，表明3种疾病中的1种。严重程度阶段之间的过渡也evaluated.Results：20325受益人在1991年，10476可用于分析，在1999年。糖尿病患病率从1991年的14.5%上升到1999年的25.6%，糖尿病患者中的糖尿病视网膜病变从6.9%上升到17.4%。原发性开角型青光眼从4.6%增加到13.8%。疑似青光眼的比例从1.5%增加到6.5%，窄角型青光眼的比例也增加了（0.7%-2.7%）。年龄相关性黄斑变性的患病率从5.0%上升到27.1%。结论：随着年龄的增长，老年人慢性眼病的临床诊断率显著增加，老年人慢性眼病的患病率也随之增加。在9年结束时，近一半的幸存医疗保险受益人至少患有其中一种疾病。
Objective: To describe the prevalence across time of 3 chronic eye diseases among a representative cohort of elderly subjects.Study Design: Longitudinal observation of Medicare claims.Population: A random sample of Medicare beneficiaries 65 years and older, nationally representative at baseline.Main Outcome Measures: Diagnosis of diabetic retinopathy, glaucoma, and age-related macular degeneration.Methods: Beneficiaries were followed from 1991 to 1999 unless mortality or enrollment in a health maintenance organization for 6 or more months in a year intervened. Claims data were analyzed for the presence of codes from the International Classification of Diseases, Ninth Revision, Clinical Modification, indicating 1 of the 3 conditions. Transitions between severity stages were also evaluated.Results: Of 20325 beneficiaries in 1991, 10476 were available for analysis in 1999. The prevalence of diabetes mellitus increased from 14.5% in 1991 to 25.6% by 1999, with diabetic retinopathy among persons with diabetes mellitus increasing from 6.9% to 17.4%. Primary open-angle glaucoma increased from 4.6% to 13.8%. The percentage of glaucoma suspects increased from 1.5% to 6.5%, as did the percentage of narrow-angle glaucoma (0.7%-2.7%). The prevalence of age-related macular degeneration increased from 5.0% to 27.1%. Overall, the proportion of subjects with at least 1 of these 3 diseases increased from 13.4% to 45.4%.Conclusions: The clinical diagnosis of major chronic eye diseases associated with aging increased dramatically in a longitudinal sample. At the end of 9 years, nearly half of the surviving Medicare beneficiaries had at least 1 of these diseases.