Influence of urethane anesthesia on neural processing in the auditory cortex analogue of a songbird
Influence of urethane anesthesia on neural processing in the auditory cortex analogue of a songbird
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DOI：
10.1016/0378-5955(96)00038-x
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发表时间：
1996-07-01
期刊：
影响因子：
2.8
通讯作者：
Leppelsack, HJ
中科院分区：
文献类型：
--
作者：
Capsius, B;Leppelsack, HJ
听觉反应区的功能地图来自于多单位记录在尾侧端脑的椋鸟（Sturnus vulgaris L.）。在听觉皮层模拟物上放置了一个规则的记录点网格，水平距离为200 μ m，垂直距离为100 μ m。在一个平面内，首先在清醒的鸟中进行听觉反应的映射，然后在氨基甲酸乙酯麻醉下重复。两种实验方法的数据差异很大。氨基甲酸乙酯显著降低自发放电率。在麻醉状态下，所有听觉亚单位的抑制都降低。兴奋受到的影响较小。根据兴奋性反应的变化，将8个听觉亚中心分为3组。在第一组中，“开”和持续的兴奋变化很弱。这些区域被认为接受间脑的直接输入。在第二组中，“开”和持续的兴奋大大减少。这些次中心似乎接受来自前脑其他区域的投射。在第三组的亚基中，持续兴奋的增加与抑制的减少相关。在某些特定的中枢中，不同的自然呼唤，例如鸟自己的歌声，在麻醉状态下会引起比其他刺激更强烈的反应。
Functional maps of auditory response areas were derived from multi-unit recordings in the caudal telencephalon of the starling (Sturnus vulgaris L.). A regular grid of recording sites with distances of 200 mu m horizontally and 100 mu m vertically was placed over the auditory cortex analogue. Within one plane, mapping of auditory responses was first performed in the awake bird and then repeated under urethane anesthesia The data from both experimental approaches differ considerably. Urethane reduces the spontaneous discharge rate significantly. Under anesthesia, inhibition decreases in all auditory subunits. Excitation is less affected. Eight auditory subcenters were divided into three groups according to the changes in their excitatory responses. In the first group 'on' and sustained excitation changed only weakly. These areas are thought to receive direct inputs from the diencephalon. In the second group,'on' and sustained excitation are substantially reduced. These subcenters seem to receive projections from other forebrain areas. In subunits of the third group, an increase in sustained excitation is correlated to a decrease in inhibition. Within some specific centers, distinct natural calls for example the bird's own song, elicit stronger responses under anesthesia than other stimuli.