Risk factors for elevated Intraocular pressure in uveitis
Risk factors for elevated Intraocular pressure in uveitis
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DOI：
10.1097/00061198-200404000-00003
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发表时间：
2004-04-01
影响因子：
2
通讯作者：
Lightman, SL
中科院分区：
文献类型：
--
作者：
Herbert, HM;Viswanathan, A;Lightman, SL
Purpose: To determine the prevalence of raised intraocular pressure (TOP) in patients with uveitis and to identify risk factors for raised TOP in patients with uveitis.Patients and Methods: Consecutive case notes of 257 patients (402 eyes) attending a specialist uveitis clinic during a three-month period were reviewed. Patients with raised TOP were identified and further evaluated. Risk factors for raised TOP were determined.Results: The prevalence of raised TOP in the study eyes was 41.8%. The prevalence of raised TOP requiring treatment was 29.8%. Raised TOP was found in 26.0% of eyes with acute uveitis and 46.1% of eyes with chronic uveitis. This difference was significant (P = 0.002). Similarly the prevalence of raised TOP requiring treatment in acute and chronic uveitis was 15.1% and 33.8%, respectively. This difference was also significant (P = 0.002). Active inflammation was significantly associated with raised TOP (P = 0.031). Steroid usage, increasing age, and number of years since diagnosis were significantly correlated with raised TOP (P = 0.008, P = 0.022, and P = 0.006, respectively); 9.6% of the study eyes developed glaucoma. The majority of these eyes (69.7%) were treated medically. The remainder (30.3%) required both medical and surgical management.Conclusion: Raised TOP is significantly more common in patients with chronic intraocular inflammation than those with acute uveitis. Risk factors for elevated TOP that should enable closer monitoring of 'at-risk' eyes have been identified.
