Working hours, sleep duration and the risk of acute coronary heart disease: A case-control study of middle-aged men in Taiwan
Working hours, sleep duration and the risk of acute coronary heart disease: A case-control study of middle-aged men in Taiwan
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DOI：
10.1016/j.ijcard.2013.12.035
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发表时间：
2014-02-15
影响因子：
3.5
通讯作者：
Su, Ta-Chen
中科院分区：
文献类型：
--
作者：
Cheng, Yawen;Du, Chung-Li;Su, Ta-Chen
背景资料：本研究旨在探讨是否长时间工作和睡眠时间短与急性心肌梗死（AMI）或严重冠心病（SCHD）的风险增加，独立于既定的心理社会工作相关factors.Methods：病例对照研究进行。病例为322例男性，年龄< 60岁，从事经济活动，在2008-2011年期间因首次诊断的AMI或SCHD住院，其中134例确诊为AMI，其他188例为血管造影确诊的SCHD。对照组为644名男性，他们来自全国性调查，并与年龄，教育和居住地区的病例相匹配。计算总CHD和确诊AMI与平均每周工作时间和每日睡眠时间的比值比。平均工作时间超过60小时/周的男性患冠心病的风险显著增加与每周工作时间在40-48 h之间者相比，每日睡眠时间少于6 h者比睡眠时间在6-9 h者患冠心病的危险性增加（OR = 3.0）。限制确认AMI产生了更大的风险，这些协会仍然与调整吸烟状况，身体质量指数和心理社会工作因素，包括工作需求，工作控制，工作场所的正义，工作不安全和轮班work.Conclusion：结果支持这一假设，即长时间工作和短睡眠时间有助于独立的男性心血管疾病的风险。(C)2013爱思唯尔爱尔兰有限公司版权所有。
Background: This study aimed to examine whether long working hours and short sleep duration were associated with an increased risk of acute myocardial infarction (AMI) or severe coronary heart diseases (SCHD), independent of established psychosocial work-related factors.Methods: A case-control study was conducted. Cases were 322 men, aged < 60 years and economically active, who were admitted to hospital with a first diagnosed AMI or SCHD during 2008-2011, of whom 134 were confirmed AMI and the other 188 were angiography-confirmed SCHD. Controls were 644 men who were drawn from a national survey and were matched to the cases on age, education and area of residence. Odds ratios of total CHD and confirmed AMI in relation to average weekly working hours and daily hours of sleep were calculated.Results: Men with average working hours longer than 60 h/week were found to have significantly increased risks for total CHD (OR = 2.2) as compared to those with weekly working hours in 40-48 h, and those with daily hours of sleep fewer than 6 h were found to have increased risks for CHD (OR = 3.0) as compared to those with sleeping hours in 6-9 h. Restriction to confirmed AMI yielded a greater risk and these associations remained consistent with adjustment of smoking status, body mass index and psychosocial work factors including job demands, job control, workplace justice, job insecurity and shift work.Conclusion: The results support the hypothesis that long working hours and short sleep duration contribute independently to the risk of cardiovascular diseases in men. (C) 2013 Elsevier Ireland Ltd. All rights reserved.