Psychosocial consequences in the Danish randomised controlled lung cancer screening trial (DLCST)
Psychosocial consequences in the Danish randomised controlled lung cancer screening trial (DLCST)
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DOI：
10.1016/j.lungcan.2014.11.003
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发表时间：
2015-01-01
期刊：
影响因子：
5.3
通讯作者：
Brodersen, J.
中科院分区：
文献类型：
--
作者：
Rasmussen, Jakob F.;Siersma, V.;Brodersen, J.
目的：测量丹麦肺癌筛查试验 (DLCST) 中的心理社会后果，并比较计算机断层扫描 (CT) 组和对照组之间的心理后果。 材料和方法：本研究是一项单中心随机对照试验，每年进行五轮筛查。年龄 50-70 岁的健康当前或以前的重度吸烟者（男性和女性）按 1:1 随机分为 CR 组和对照组。重度吸烟者的定义是吸烟时间 >= 20 包年，前吸烟者的定义是戒烟 0，p < .0001（对于 4 个可能量表中的 3 个）。在第 2-5 轮期间，与 CT 组相比，对照组在 9 个量表中的 7 个中经历了显着更多的负面心理社会后果（平均 Delta 得分 >0 且 p < .033）。结论：与基线心理社会概况相比，肺癌 CT 筛查试验在 CT 组和对照组中引起了更多的负面心理社会反应。与对照组相比，CT 组经历的负面心理社会后果较少，这可能是由于筛查结果正常的人感到放心。 (C) 2014 Elsevier Ireland Ltd. 保留所有权利。
Objectives: To measure the psychosocial consequences in the Danish lung cancer screening trial (DLCST) and compare those between the computed tomography (CT) group and the control group.Materials and methods: This study was a single centre randomised controlled trial with five annual screening rounds. Healthy current or former heavy smokers aged 50-70 years (men and women) were randomised 1:1 to a cr group and a control group. Heavy smokers were defined by having smoked >= 20 pack years and former smokers by being abstinent 0, p < .0001 for 3 of 4 possible scales). During rounds 2-5 the control group experienced significantly more negative psychosocial consequences in seven of nine scales compared with the CT group (mean Delta score >0 and p < .033).Conclusions: Lung cancer CT-screening trials induced more negative psychosocial reactions in both the CT group and the control group compared with the baseline psychosocial profile. The CT group experienced less negative psychosocial consequences compared with the control group, which might be explained by reassurance among those with normal screening results. (C) 2014 Elsevier Ireland Ltd. All rights reserved.