Major and Minor Electrocardiographic Abnormalities and Their Association With Underlying Cardiovascular Disease and Risk Factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos)
Major and Minor Electrocardiographic Abnormalities and Their Association With Underlying Cardiovascular Disease and Risk Factors in Hispanics/Latinos (from the Hispanic Community Health Study/Study of Latinos)
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DOI：
10.1016/j.amjcard.2013.08.004
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发表时间：
2013-11-15
影响因子：
2.8
通讯作者：
Daviglus, Martha L.
中科院分区：
文献类型：
--
作者：
Denes, Pablo;Garside, Daniel B.;Daviglus, Martha L.
心电图 (ECG) 异常与心血管疾病和危险因素的关联已在白人和非裔美国人中进行了广泛研究。西班牙裔/拉丁裔尚未报道类似数据。西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 是一项多中心、基于社区的前瞻性队列研究，研究对象为 18 至 74 岁、自认为是西班牙裔/拉丁裔的不同背景的男性和女性。参与者 (n = 16,415) 于 2008 年 3 月至 2011 年 6 月期间入组。我们描述了轻微和主要心电图异常的患病率，并检查了它们与心血管疾病和危险因素的横截面关联。明尼苏达州规范标准用于定义轻微和主要心电图异常。先前的心血管疾病和危险因素是基于基线检查时获得的数据。男性和女性之间流行的心电图结果存在显着差异。 9.2%（95% 置信区间 8.3 至 10.1）的男性和 6.6%（95% 置信区间 5.8 至 7.3）的女性存在主要心电图异常（男性和女性均存在心血管危险因素和普遍的心血管疾病，p = 3）。不同群体之间发现主要心电图异常存在显着差异；相比之下，波多黎各人和多米尼加人有更多的主要异常 与墨西哥男人和女人。总之，在一大群西班牙裔/拉丁裔男性和女性中，主要异常的患病率较低，但在男性和女性中都观察到主要心电图异常与心血管疾病和危险因素之间存在很强的关联。 (C) 2013 Elsevier Inc. 保留所有权利。
The association of electrocardiographic (ECG) abnormalities with cardiovascular disease and risk factors has been extensively studied in whites and African-Americans. Comparable data have not been reported in Hispanics/Latinos. The Hispanic Community Health Study/Study of Latinos (HCHS/SOL) is a multicenter, community-based, prospective cohort study of men and women of diverse backgrounds aged 18 to 74 years who self-identified as Hispanic/Latinos. Participants (n = 16,415) enrolled from March 2008 to June 2011. We describe the prevalence of minor and major ECG abnormalities and examined their cross-sectional associations with cardiovascular disease and risk factors. The Minnesota code criteria were used to define minor and major ECG abnormalities. Previous cardiovascular disease and risk factors were based on data obtained at baseline examination. Significant differences in prevalent ECG findings were found between men and women. Major ECG abnormalities were present in 9.2% (95% confidence interval 8.3 to 10.1) of men and 6.6% (95% confidence interval 5.8 to 7.3) of women (p = 3 cardiovascular risk factors, and prevalent cardiovascular disease, in both men and women. Significant differences in major ECG abnormalities were found among the varying groups; Puerto Ricans and Dominicans had more major abnormalities compared with Mexican men and women. In conclusion, in a large cohort of Hispanic/Latino men and women, prevalence of major abnormalities was low, yet strong associations of major ECG abnormalities with cardiovascular disease and risk factors were observed in both men and women. (C) 2013 Elsevier Inc. All rights reserved.