Neogrifolin derivatives possessing anti-oxidative activity from the mushroom Albatrellus ovinus
Neogrifolin derivatives possessing anti-oxidative activity from the mushroom Albatrellus ovinus
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DOI：
10.1016/s0031-9422(02)00050-x
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发表时间：
2002-04-01
期刊：
影响因子：
3.8
通讯作者：
Asakawa, Y
中科院分区：
文献类型：
--
作者：
Nukata, M;Hashimoto, T;Asakawa, Y
从日本产野蘑菇Albatrellus ovinas中分离得到3个新灰树花素衍生物，即3-羟基新灰树花素、1-甲酰基新灰树花素和1-甲酰基-3-羟基新灰树花素沿着，以及灰树花素和新灰树花素。它们的结构通过二维NMR光谱分析和化学合成的组合来确定。3-羟基新甘草酸和1-甲酰基-3-羟基-新甘草酸显示出比α-生育酚或BHA更有效的抗氧化活性特性。(C)2002爱思唯尔科技有限公司版权所有。
Three neogrifolin derivatives, 3-hydroxyneogrifolin, 1-formylneogrifolin and 1-formyl-3-hydroxyneogrifolin along with grifolin and neogrifolin were isolated from the Japanese mushroom Albatrellus ovinas belonging to Scutigeraceae. Their structures were established by a combination of two-dimensional NMR spectroscopic analyses and by chemical synthesis. 3-Hydroxyneogrifolin and 1-formyl-3-hydroxy-neogrifolin showed more potent antioxidative activity properties than either a-tocopherol or BHA. (C) 2002 Elsevier Science Ltd. All rights reserved.