The systematic location of genes by means of crossover observations
The systematic location of genes by means of crossover observations
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DOI：
10.1086/279880
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发表时间：
1922-01-01
影响因子：
2.9
通讯作者：
Fisher, RA
中科院分区：
文献类型：
--
作者：
Fisher, RA
在染色体图谱的构建中，相邻基因之间的距离等同于它们之间观察到的交叉百分比。由于随机抽样的误差，有时由于其他令人不安的原因，在这样确定的距离之间总是出现不一致的情况。例如，在Lancefield和Metz给出的关于果蝇性染色体的重要数据[1，p.241]中，我们有以下值：
IN the construction of a chromosome map, the distances between neighboring genes are equated to the percentage of crossovers which have been observed between them. Owing to errors of random sampling, and sometimes to other disturbing causes, inconsistencies always arise between the distances so determined. For example, in the important data given by Lancefield and Metz for the sex chromosome of Drosophila willistoni [1, p. 241] we have the following values: