Scleroderma After Cosmetic Surgery
Scleroderma After Cosmetic Surgery
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整容手术后的硬皮病
DOI：
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发表时间：
1979
期刊：
影响因子：
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通讯作者：
Y. Shiokawa
中科院分区：
文献类型：
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作者：
Y. Kumagai;C. Abe;Y. Shiokawa
在9例人类辅助性疾病中，观察到4例硬皮病（3例为进行性系统性硬化症，1例为局限性硬斑病）。为了美容目的而将异物注入乳房或鼻子后 7 至 19 年，一些患者出现了人类佐剂病。在一例病例中，通过双侧乳房切除术去除了异物，对患者的临床病程没有明显影响。切除的乳房的组织病理学结果显示异物肉芽肿伴钙化。经鉴定，注入的物质是液体和固体石蜡的混合物。人类佐剂疾病可能是由作为佐剂的注射外来物质激活的长期超敏反应引起的。
In 9 cases of human adjuvant disease, 4 cases of scleroderma (3 progressive systemic sclerosis and 1 localized morphea) were observed. Seven to 19 years after injection of foreign substances into the breasts or nose for cosmetic purposes, some patients developed human adjuvant disease. In one case the foreign substances were removed by bilateral mastectomy with no discernible effects on the patient's clinical course. Histopathologic findings of the removed breasts demonstrated foreign body granulomas with calcification. The injected substance was identified as a mixture of liquid and solid paraffin. Human adjuvant disease might be caused by prolonged hypersensitization activated by the injected foreign materials which act as an adjuvant.