Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study
Bone mineral density and dietary patterns in older adults: the Framingham Osteoporosis Study
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DOI：
10.1093/ajcn/76.1.245
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发表时间：
2002-07-01
影响因子：
7.1
通讯作者：
Kiel, DP
中科院分区：
文献类型：
--
作者：
Tucker, KL;Chen, HL;Kiel, DP
背景：已知几种营养素会影响骨密度（BMD）。然而，这些营养素发生在一起的食物和饮食模式，饮食选择的整体影响还没有很好地understood.Objective：我们评估了饮食模式和BMD在老年adults.Design之间的关联：原始心脏研究对象，907年龄69-93 y完成的食物频率问卷的一部分，骨质疏松症的研究。我们通过聚类分析定义了饮食模式。用双光子骨密度仪测量右股骨近端（股骨颈、转子、Ward区）的BMD，用单光子骨密度仪测量桡骨干33%的BMD。我们回归BMD的措施到集群变量，调整潜在的混杂因素。结果：六种饮食模式被确定，从肉类，奶制品和面包的摄入量相对较大的比例;肉类和甜烘焙产品;甜烘焙产品;酒精;糖果;水果，蔬菜和谷物。在调整多重比较后，最后一组男性在髋部部位的BMD显著（P = 0.05）高于其他2-4组，在桡骨部位的BMD显著高于糖果组。在4个部位中的3个部位，糖果组的男性BMD显著低于水果、蔬菜和谷物组（P < 0.05）。除一组外，糖果组女性桡骨BMD显著低于其他组（P < 0.01）。结论：饮食模式与BMD相关。高水果和蔬菜摄入量似乎对男性有保护作用。高糖果消费与男性和女性的低BMD相关。
Background: Several nutrients are known to affect bone mineral density (BMD). However, these nutrients occur together in foods and dietary patterns, and the overall effects of dietary choices are not well understood.Objective: We evaluated associations between dietary patterns and BMD in older adults.Design: Of the original Framingham Heart Study subjects, 907 aged 69-93 y completed food-frequency questionnaires as part of an osteoporosis study. We defined dietary patterns by cluster analysis. BMD was measured at the proximal right femur (femoral neck, trochanter, Ward's area) with a dual-photon absorptiometer and at the 33% radial shaft with a single-photon absorptiometer. We regressed BMD measures onto the cluster variable, adjusting for potential confounders.Results: Six dietary patterns were identified, with relatively Greater proportions of intake from meat, dairy, and bread; meat and sweet baked products; sweet baked products; alcohol; candy; and fruit, vegetables, and cereal. After adjustment for multiple comparisons, men in the last group had significantly (P = 0.05) greater BMD than did 2-4 other groups at the hip sites and the candy group at the radius. Men in the candy group had significantly (P < 0.05) lower BMD than did those in the fruit, vegetables, and cereal group for 3 of the 4 sites. Women in the candy group had significantly (P < 0.01) lower BMD than did all but one other group at the radius.Conclusions: Dietary pattern is associated with BMD. High fruit and vegetable intake appears to be protective in men. High candy consumption was associated with low BMD in both men and women.