Resection of metastatic renal cell carcinoma
Resection of metastatic renal cell carcinoma
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DOI：
10.1200/jco.1998.16.6.2261
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发表时间：
1998-06-01
影响因子：
45.3
通讯作者：
Brady, MS
中科院分区：
文献类型：
--
作者：
Kavolius, JP;Mastorakos, DP;Brady, MS
目的：肾细胞癌（RCC）孤立性转移瘤切除术的5年生存率为35%~ 50%，选择标准不明确。患者和方法：我们回顾性分析了1980 ~ 1993年278例复发性RCC患者的治疗经验。278例患者中有141例因首次复发接受了根治性转移切除术（44%的5年总生存率[OS]），70例患者接受了非治愈性手术（5年OS率为14%），67例患者接受了非手术治疗无病期（DFI）大于12个月与12个月或更短（5年OS率55% vs9%; P
Purpose: Resection of solitary metastases from renal cell carcinoma (RCC) is associated with a 5-year survival rate of 35% to 50%, Selection criteria are not well defined.Patients and Methods: We retrospectively analyzed our experience with 278 patients with recurrent RCC from 1980 to 1993,Results: One hundred forty-one of 278 patients underwent a curative metastectomy for their first recurrence (44% 5-year overall survival [OS] rate), 70 patients underwent noncurative surgery (14% 5-year OS rate), and 67 patients were treated nonsurgically (11% 5-year OS rate), Favorable features for survival were a disease-free interval (DFI) greater than 12 months versus 12 months or less (55% v 9% 5-year OS rate; P