Training Surface and Intensity: Inflammation, Hemolysis, and Hepcidin Expression
Training Surface and Intensity: Inflammation, Hemolysis, and Hepcidin Expression
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DOI：
10.1249/mss.0b013e318192ce58
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发表时间：
2009-05-01
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影响因子：
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通讯作者：
Trinder, Debbie
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文献类型：
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作者：
Peeling, Peter;Dawson, Brian;Trinder, Debbie
Peeling，P.，B。道森角古德曼兰德斯T.维格林克W. SWINKELS和D. TRINDER。训练表面和强度：炎症、溶血和铁调素表达。医学科学体育锻炼：第41卷，第5期，第100页。1138-1145，2009。目的：本研究评估了训练强度和地面类型对跑步过程中溶血、炎症和铁调素活性的影响。研究方法：10名训练有素的男性耐力运动员完成了一项分级运动测试，在草地（GRASS）和沥青路面（ROAD）上以75%-80%的峰值（V）超过dotO（2）跑步速度连续跑10公里，并以90%-95%的峰值（V）超过dotO（2）跑步速度进行10 x 1公里的间歇跑（INT）。在运动前、运动后即刻、运动后3 h和运动后24 h采集静脉血和尿样。分析血清样品的IL-6、游离血红蛋白（Hb）、触珠蛋白（Hp）、铁和铁蛋白的循环水平。分析尿样中铁调素表达的变化。结果如下：运动后IL-6和游离Hb均显著高于运动前，而血清Hp显著低于运动前（P < 0.05）。INT组IL-6水平和游离Hb较基线的变化显著高于GRASS组（P < 0.05）。GRASS和ROAD两种训练面的训练效果无显著性差异（P > 0.05）。血清铁和铁蛋白在三种条件下运动后均显著升高（P < 0.05），但试验间无差异。结论：更大的跑步强度导致更多的炎症和溶血，但这些变量不受训练表面类型的影响。
PEELING, P., B. DAWSON, C. GOODMAN, G. LANDERS, E. T. WIEGERINCK, D. W. SWINKELS, and D. TRINDER. Training Surface and Intensity: Inflammation, Hemolysis, and Hepcidin Expression. Med. Sci. Sports Exerc., Vol. 41, No. 5, pp. 1138-1145, 2009. Purpose: This investigation assessed the effects of training intensity and ground surface type on hemolysis, inflammation, and hepcidin activity during running. Methods: Ten highly trained male endurance athletes completed a graded exercise test, two continuous 10-km runs on a grass (GRASS) and a bitumen road surface (ROAD) at 75%-80% peak (V) over dotO(2) running velocity, and a 10 x 1-km interval running session (INT) at 90%-95% of the peak (V) over dotO(2), running velocity. Venous blood and urine samples were collected before, immediately after, and at 3 and 24 h after exercise. Serum samples were analyzed for circulating levels of IL-6, free hemoglobin (Hb), haptoglobin (Hp), iron, and ferritin. Urine samples were analyzed for changes in hepcidin expression. Results: After running, the IL-6 and free Hb were significantly greater, and serum Hp was significantly lower than preexercise values in all three conditions (P < 0.05). Furthermore, IL-6 levels and the change in free Hb from baseline were significantly greater in the INT compared with those in the GRASS (P < 0.05). There were no differences between the GRASS and ROAD training surfaces (P > 0.05). Serum iron and ferritin were significantly increased after exercise in all three conditions (P < 0.05) but were not-different between trials. Conclusion: Greater running intensities incur more inflammation and hemolysis, but these variables were not affected by the surface type trained upon.