Early- to Late-Life Environmental Factors and Late-Life Global Cognition: The SONIC study
Early- to Late-Life Environmental Factors and Late-Life Global Cognition: The SONIC study
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早期到后期的环境因素和晚期全球认知：声音研究
DOI：
10.1093/geroni/igaa057.1169
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发表时间：
2020-12-16
影响因子：
7
通讯作者：
Ishizaki T
中科院分区：
文献类型：
--
作者：
Ishioka Y;Gondo Y;Masui Y;Nakagawa T;Ogawa M;Inagaki H;Yasumoto S;Ishizaki T
据报道，整个生命过程中的生活环境，如参与晚年休闲活动（LA），主要职业和早期教育，与更好的晚年认知结果相关。然而，很少有研究包括所有这些因素，从过去到现在，由于耗时的程序来衡量所有因素。本研究考察了（1）在考虑了其他生活环境后，晚年生活是否与更好的晚年认知相关;（2）职业、教育和儿童智商是否通过晚年生活间接影响晚年认知。我们使用了SONIC研究中70岁和80岁人群的基线数据（N = 1721）。整体认知使用蒙特利尔认知评估进行测量。至于法律事务，要求参与者就他们参与158项活动的问题回答是/否。在分析中使用了代表LA的潜在因子。我们回顾性地评估了数据、人员和事物工作的复杂性。作为早期生活环境，小学期间的教育和语言和算术能力也被纳入分析。控制年龄和性别。结构方程模型显示，即使在控制了所有过去因素后，晚年LA也与更高的整体认知显着相关（RMSEA = 0.050，GFI = 0.973，AGFI = 0.947）。索贝尔测验显示，职业、教育和儿童能力对认知功能有显著的间接影响。结果在不同年龄和性别之间都很稳定。有人建议，在LA的参与解释了晚年认知功能的个体差异。
Life environment across the life course—such as engagement in late-life leisure activity (LA), primary occupation, and early-life education—have been reported to be associated with better late-life cognitive outcomes. However, few studies have included all these factors from the past to the present due to the time-consuming procedure to measure all factors. This study examined (1) whether late-life LA is associated with better late-life cognition, after considering other life environments and (2) whether occupation, education, and childhood intelligence quotient have indirect effects on the late-life cognition through late-life LA. We used baseline data from the groups of 70- and 80-year-olds in the SONIC study (N = 1721 ). Global cognition was measured using the Montreal Cognitive Assessment. As for LA, participants were asked for yes/no answers to questions regarding their engagement in 158 activities. A latent factor representing LA was used in the analyses. We retrospectively evaluated the complexity of work with data, people, and things. As early-life environments, education and language and arithmetic abilities during elementary school were included in the analyses. Age and gender were controlled. A structural equation model showed that late-life LA was significantly associated with higher global cognition, even after controlling for all past factors (RMSEA = .050, GFI = .973, AGFI = .947). Sobel tests showed significant indirect effects of occupation, education, and childhood abilities on cognitive function. Results were robust across age and gender. It is suggested that engagement in LA explains individual differences in late-life cognitive function.