Responses of guinea pig primary vestibular neurons to clicks

Responses of guinea pig primary vestibular neurons to clicks
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豚鼠初级前庭神经元对咔嗒声的反应

DOI:
10.1007/bf00241975
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发表时间:
2004
影响因子:
2
通讯作者:
G. Halmágyi
G. Halmágyi
中科院分区:
医学4区
文献类型:
--
作者:
T. Murofushi;I. Curthoys;A. Topple;J. Colebatch;G. Halmágyi

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用细胞外记录法研究了麻醉豚鼠前庭神经单个神经元对高强度短声的反应。前庭神经上级分支后股或下分支的102个神经元在短潜伏期内被强烈的短声激活。激活的潜伏期很短(中位数0.9 ms),阈值很高:唤起这些细胞反应的点击强度比听觉脑干反应阈值高出约60 dB。动物被倾斜和旋转,以确定生理上的感觉区域的迷路从激活的神经元起源。17个神经元对静态倾斜和点击做出反应。这些结果表明,前庭感受器,可能是耳石,响应点击强度对应于那些在前庭-结肠通路的一个新的临床测试。
Responses of single neurons in the vestibular nerve to high-intensity clicks were studied by extracellular recording in anaesthetised guinea pigs. One hundred and two neurons in the posterior division of the superior branch or in the inferior branch of the vestibular nerve were activated at short latency by intense clicks. The latency of activation was short (median 0.9 ms) and the threshold was high: the click intensity for evoking the response of these cells was around 60 dB above the auditory brainstem response threshold. Animals were tilted and rotated to identify physiologically the sensory region of the labyrinth from which the activated neurons originated. Seventeen neurons responded to static tilt as well as clicks. These results show that vestibular receptors, probably the otoliths, respond to clicks at intensities corresponding to those used in a new clinical test of the vestibulo-collic pathway.
DOI: 10.1016/0013-4694(83)90259-6
发表时间: 1983
期刊: Electroencephalography and clinical neurophysiology
影响因子: --
作者:
Wada,SI;Starr,A
通讯作者: Starr,A