Cell patterning using microstructured ferromagnetic thin films
Cell patterning using microstructured ferromagnetic thin films
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DOI：
10.1063/1.3383229
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发表时间：
2010-05-03
影响因子：
4
通讯作者：
Wei, Zung-Hang
中科院分区：
文献类型：
--
作者：
Lai, Mei-Feng;Chen, Chia-Yi;Wei, Zung-Hang
通过控制微结构铁磁薄膜中的微磁状态，证明了磁性单元图案化。通过磁泳实验可以确定通过内吞进入细胞的磁性纳米颗粒的数量，并且发现其依赖于共培养的细胞外磁性纳米颗粒浓度。在锯齿形磁性薄膜中，在不同方向施加场后，沉积态和还原态的磁性薄膜的单元图案化效果不同。同心环的剩余状态提出了细胞图案化。通过选择性地改变磁场方向，可以将细胞按顺序排列在任何位置。(C)2010年美国物理学会。[doi：10.1063/1.3383229]
Magnetic cell patterning is demonstrated through controlling the micromagnetic states in microstructured ferromagnetic thin films. The number of magnetic nanoparticles entering the cells by endocytosis can be determined by magnetophoresis experiment and is found to be dependent of the cocultured extracellular magnetic nanoparticles concentrations. In zigzag magnetic films the effects of cell patterning differ for magnetic films at as-deposited state and at remanent states after applying fields in different directions. Remanent states of concentric rings are proposed for cell patterning. Cells can be arranged at any positions in sequence by selectively changing the magnetic field directions. (C) 2010 American Institute of Physics. [doi:10.1063/1.3383229]