SEVERE DISTURBANCE OF HIGHER COGNITION AFTER BILATERAL FRONTAL-LOBE ABLATION - PATIENT EVR
SEVERE DISTURBANCE OF HIGHER COGNITION AFTER BILATERAL FRONTAL-LOBE ABLATION - PATIENT EVR
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DOI：
10.1212/wnl.35.12.1731
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发表时间：
1985-01-01
期刊：
影响因子：
9.9
通讯作者：
DAMASIO, AR
中科院分区：
文献类型：
--
作者：
ESLINGER, PJ;DAMASIO, AR
在双侧眼眶和下内侧额叶皮质消融后，患者的行为发生了深刻的变化，并保持稳定8年。虽然他不能履行个人和职业责任，但他的“可测量”智力是上级的，因此他被认为是一个“装病者”。“神经系统和神经心理学检查在其他方面完好无损。CT、MRI和SPET显示眼眶和下内侧额叶皮质的局部病变。所有其他脑区的结构和放射性模式均正常。这种动机和复杂的社会行为的损害在对照病例中没有看到上级内侧或背外侧额叶病变。
After bilateral ablation of orbital and lower mesial frontal cortices, a patient had profound changes of behavior that have remained stable for 8 years. Although he could not meet personal and professional responsibilities, his "measurable" intelligence was superior, and he was therefore considered a "malingerer." Neurologic and neuropsychological examinations were otherwise intact. CT, MRI, and SPET revealed a localized lesion of the orbital and lower mesial frontal cortices. All other cerebral areas had normal structure and radioactivity patterns. Such impairments of motivation and complex social behavior were not seen in control cases with superior mesial or dorsolateral frontal lesions.