Factors affecting angiotensin II concentrations in the human infant at birth.
Factors affecting angiotensin II concentrations in the human infant at birth.
复制标题
影响人类婴儿出生时血管紧张素 II 浓度的因素。
DOI：
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发表时间：
1977
期刊：
影响因子：
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通讯作者：
E. Symonds
中科院分区：
文献类型：
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作者：
F. Broughton Pipkin;E. Symonds
1.一种放射免疫测定法测量血管紧张素II在1毫升血浆已被开发和用于测量血管紧张素II在产妇外周血，脐带静脉和脐带动脉血中的45例患者在分娩。2.在阴道分娩的婴儿中，脐带静脉和脐带动脉血管紧张素II浓度显著高于母体静脉血浓度。脐带静脉和脐带动脉血管紧张素II浓度与母体血管紧张素II浓度之间存在显著相关性。3.脐静脉血管紧张素II浓度显着高于脐带动脉血中的阴道分娩的婴儿，但不是在那些交付的下段剖腹产。这表明，在分娩过程中，胎盘可能有助于胎儿血管紧张素II的浓度。4.妊娠期高血压疾病患者的母体和脐带静脉血管紧张素II浓度显著高于妊娠期血压正常者。5.脐带静脉血管紧张素II的浓度显着增加的第二产程的持续时间。
1. A radioimmunoassay for the measurement of angiotensin II in 1 ml of plasma has been developed and used to measure angiotensin II in maternal peripheral, cord venous and cord arterial blood in 45 patients at delivery. 2. In babies delivered vaginally, cord venous and cord arterial concentrations of angiotensin II were significantly higher than maternal venous blood concentrations. There was a significant relationship between both cord venous and cord arterial concentrations and maternal concentrations of angiotensin II. 3. Cord venous concentrations of angiotensin II were significantly greater than those in cord arterial blood in babies delivered vaginally but not in those delivered by lower-segment Caesarean section. This suggests the possibility that, during labour, the placenta may contribute to foetal concentrations of angiotensin II. 4. Maternal and cord venous concentrations of angiotensin II were significantly higher in patients with hypertensive disease of pregnancy than in those who had remained normotensive throughout pregnancy. 5. Cord venous concentrations of angiotensin II increased significantly with increasing duration of the second stage of labour.