Activation of molecular oxygen by flavins and flavoproteins.
Activation of molecular oxygen by flavins and flavoproteins.
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发表时间：
1994-09
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通讯作者：
V. Massey
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作者：
V. Massey
基本上是不可逆转的。在自由溶液中，反应很慢，因为自旋反转与单重态还原黄素与三重态0和络合物的反应有关，如下所述。对于黄素蛋白，与0的反应可能快或慢几个数量级，这取决于特定的黄素蛋白或它所属的黄素蛋白的类别。显然，还原的黄素与0的反应活性受到其所在的蛋白质环境的调节，无论是反应速度还是反应产物(见参考文献)。1以进行更详细的审查)。
is essentially irreversible. In free solution the reaction is slow because of spin inversion associated with the reaction of singlet reduced flavin with triplet 0, and complex, as described below. With flavoproteins the reaction with 0, may be orders of magnitude faster or slower, depending on the specific flavoprotein or the class of flavoprotein to which i t belongs. Clearly the reactivity of the reduced flavin with 0, is modulated by the protein environment in which i t is located, both in terms of rates and products of the reaction (see Ref. 1 for a more detailed review).