Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a Peltier-cooled sample stage.

Infrared atmospheric pressure MALDI ion trap mass spectrometry of frozen samples using a Peltier-cooled sample stage.
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DOI:
10.1021/ac049575v
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发表时间:
2004-08
影响因子:
7.4
通讯作者:
Christopher E Von Seggern;B. Gardner;R. Cotter
Christopher E Von Seggern;B. Gardner;R. Cotter
中科院分区:
化学1区
文献类型:
--
作者:
Christopher E Von Seggern;B. Gardner;R. Cotter

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Infrared atmospheric pressure matrix-assisted laser desorption/ionization on an ion trap mass spectrometer is used to analyze frozen samples generated using a Peltier-cooled sample stage. This allows for the analysis of samples in water without the addition of matrix, in near-native conditions, and with minimal loss of water due to evaporation. Analysis of frozen samples is extended to study peptides, carbohydrates, and glycolipids.