Characterizing Heat-Sensitization Responses in Suspended Moxibustion with High-Density EEG
Characterizing Heat-Sensitization Responses in Suspended Moxibustion with High-Density EEG
复制标题
用高密度脑电图表征悬灸的热敏反应
DOI：
10.1111/pme.12512
复制
发表时间：
2014-08-01
期刊：
影响因子：
3.1
通讯作者：
Yi, Ming
中科院分区：
文献类型：
--
作者：
Liao, Feifei;Zhang, Chan;Yi, Ming
目标。我们已经报道了悬灸期间的“热敏化”反应，其发生与明显更好的治疗效果相关。本研究旨在用高密度脑电图（EEG）来描述这一有趣现象的电生理特征。我们对一组慢性腰痛患者在du3艾灸治疗前、中、后分别进行脑电图记录。25名受试者中有12名在艾灸期间经历了强烈的热敏化，这伴随着theta， alpha和beta频段的功率谱密度（psd）的增加。平均功率的头皮地形图显示，θ和β PSD的变化在额中央区最为明显，而α波段的变化更为全面。此外，非敏化组和敏化组表现出不同的活动模式，热敏化诱导θ和β范围相相干性增加。这些数据是悬灸期间热敏反应的第一个客观证据，其特征是头皮脑电图的广泛振荡变化。
Objective. We have reported "heat-sensitization" responses during suspended moxibustion, whose occurrence is associated with significantly better therapeutic effects. The present study aimed to characterize the electrophysiological features of this interesting phenomenon with high-density electroencephalography (EEG).Methods. We performed EEG recording in a group of patients with chronic low back pain before, during, and after moxibustion treatment at DU3.Results. 12 out of 25 subjects experienced strong heat-sensitization during moxibustion, which was accompanied by increased power spectral densities (PSDs) at the theta, alpha, and beta frequency bands. The scalp topographies of averaged power indicated that the theta and beta PSD changes were most obvious in fronto-central regions, whereas those of the alpha band were more global. In addition, nonsensitized and sensitized groups showed distinct activity patterns, with heat-sensitization inducing increased phase coherence at the theta and beta ranges.Conclusions. These data were the first objective evidence of heat-sensitization responses during suspended moxibustion, which were characterized by widespread oscillatory changes in scalp EEG.