Feasibility of applying ultrasound strain imaging to detect renal transplant chronic allograft nephropathy.
Feasibility of applying ultrasound strain imaging to detect renal transplant chronic allograft nephropathy.
复制标题
应用超声应变成像检测肾移植慢性同种移植肾病的可行性。
DOI：
10.1111/j.1523-1755.2004.00435.x
复制
发表时间：
2004
影响因子：
19.6
通讯作者：
O'Donnell,Matthew
中科院分区：
文献类型：
--
作者：
Weitzel,WilliamF;Kim,Kang;Rubin,JonathanM;Wiggins,RogerC;Xie,Hua;Chen,Xunchang;Emelianov,StanislavY;O'Donnell,Matthew
Feasibility of applying ultrasound strain imaging to detect renal transplant chronic allograft nephropathy.Chronic renal transplant fibrosis, often termed Chronic Allograft Nephropathy, may progress undetected. Since renal fibrosis may be accompanied by a change in measurable elastic tissue properties, ultrasound strain measurements may be useful in its detection. Ultrasound strain imaging was performed for two subjects with renal transplants; one with normal renal function and one with mild renal insufficiency and biopsy demonstrated fibrosis. Subjects underwent ultrasound examination with application of a controlled deformation using phase-sensitive, two-dimensional speckle tracking to evaluate internal tissue motion to measure tissue displacement and strain. Measurements over multiple beams for an equivalent deformational stress showed there was a threefold differences in renal cortical strain between the two subjects. These data suggest that ultrasound elasticity imaging may prove useful in measuring mechanical changes related to fibrosis within the transplant kidney.
