Simulation of the behaviour of the L1 vertebra for different material properties and loading conditions.
Simulation of the behaviour of the L1 vertebra for different material properties and loading conditions.
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模拟 L1 椎骨在不同材料特性和负载条件下的行为。
DOI：
10.1080/10255842.2011.636741
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发表时间：
2013
影响因子：
1.6
通讯作者：
vanderMeulen,MarjoleinCH
中科院分区：
文献类型：
--
作者：
Erdem,Ibrahim;Truumees,Eeric;vanderMeulen,MarjoleinCH
建立胸腰段（T12-L2）和孤立L1椎体的三维有限元模型，研究材料特性和载荷条件对椎体应力和应变的作用，以预测骨折风险。从计算机断层扫描图像获得椎骨的几何形状。分离的椎骨模型包括通过位于椎骨顶部和底部的聚甲基丙烯酸甲酯板加载的L1椎骨，节段模型包括T12至L2椎骨和七个韧带、纤维椎间盘和小关节。每种模型均采用均匀和空间变化的骨组织特性进行检查。比较均匀压缩和屈曲时的应力和应变。包括材料的异质性显着降低了孤立的L1椎骨的刚度，并增加了最小主应变和应力的幅度在中间横截面。当生理载荷施加到L1椎骨时，应力和应变分布进一步改变。在段模型中，包括异质材料属性的最小主应变的大小增加了158%，在中间横截面的中心。总体而言，纳入异质性和生理载荷使屈曲时的应变幅度增加了346%，压缩时增加了273%。
Three-dimensional finite element models of the thoracolumbar junction (T12–L2) and isolated L1 vertebra were developed to investigate the role of material properties and loading conditions on vertebral stresses and strains to predict fracture risk. The geometry of the vertebrae was obtained from computed tomography images. The isolated vertebra model included an L1 vertebra loaded through polymethylmethacrylate plates located at the top and bottom of the vertebra, and the segment model included T12 to L2 vertebrae and seven ligaments, fibrous intervertebral discs and facet joints. Each model was examined with both homogeneous and spatially varying bone tissue properties. Stresses and strains were compared for uniform compression and flexion. Including material heterogeneity remarkably reduced the stiffness of the isolated L1 vertebra and increased the magnitudes of the minimum principal strains and stresses in the mid-transverse section. The stress and strain distributions further changed when physiological loading was applied to the L1 vertebra. In the segment models, including heterogeneous material properties increased the magnitude of the minimum principal strain by 158% in the centre of the mid-transverse section. Overall, the inclusion of heterogeneity and physiological loading increased the magnitude of the strains up to 346% in flexion and 273% in compression.