A common cognitive profile in elderly fallers and in patients with Parkinson's disease: The prominence of impaired executive function and attention

A common cognitive profile in elderly fallers and in patients with Parkinson's disease: The prominence of impaired executive function and attention
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DOI:
10.1080/03610730600875817
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发表时间:
2006-10-01
影响因子:
1.8
通讯作者:
Simon, Ely S.
Simon, Ely S.
中科院分区:
医学4区
文献类型:
--
作者:
Hausdorff, Jeffrey M.;Doniger, Glen M.;Simon, Ely S.

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本研究使用计算机化电池检查了老年跌倒者相对于健康老年人对照组和帕金森病(PD)患者(阳性对照组)的认知特征。跌倒者在执行功能、注意力和运动技能方面比对照组表现更差,但在记忆、信息处理和简易精神状态检查方面表现更好。PD患者的特征相似。然而,与PD患者不同,跌倒者的反应时间异常不一致。这些发现表明,老年跌倒者可能有一个独特的认知处理缺陷(即,响应时间的可变性),并强调执行功能和注意力作为跌倒风险筛查和干预的潜在目标的重要性。
The present study examined the cognitive profile of elderly fallers relative to healthy elderly controls and patients with Parkinson's disease ( PD), a positive-control group, using a computerized battery. Fallers performed more poorly than controls on executive function, attention, and motor skills, but performed comparably on memory, information processing and the Mini-Mental State Examination. A similar profile was evident for PD patients. However, unlike PD patients, fallers were abnormally inconsistent in their reaction times. These findings indicate that elderly fallers may have a unique cognitive processing deficit ( i.e., variability of response timing) and underscore the importance of executive function and attention as potential targets for fall risk screening and interventions.