INFLUENCE OF ADRENAL CORTEX ON BODY WATER DISTRIBUTION IN RATS.
INFLUENCE OF ADRENAL CORTEX ON BODY WATER DISTRIBUTION IN RATS.
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肾上腺皮质对大鼠体内水分分布的影响。
DOI：
10.1152/ajplegacy.1965.208.4.662
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发表时间：
1965
期刊：
影响因子：
--
通讯作者：
A. Moses
中科院分区：
文献类型：
--
作者：
A. Moses
Body water distribution was determined in rats by the dilution of serum albumin-I 131 and Br 82 and by desiccation. Methylprednisolone (MP) increased the plasma and intracellular compartments and decreased the interstitial volume in intact hydrated rats. The body water moved in the opposite direction in the adrenalectomized, salt-maintained rats, and MP prevented this movement in terms of intracellular and interstitial volumes. Adrenalectomized rats which were salt depleted had an increased intracellular volume with water coming from both extracellular compartments, and MP had no effect in this group. The effect of deoxycorticosterone acetate was to increase plasma volume in the intact hydrated and in both adrenalectomized groups. The relationship between these changes in body water distribution, hematocrit, and plasma osmolality and sodium concentrations has been discussed.
