Is Health-Related Quality of Life Improving After Stroke? A Comparison of Health Utilities Indices Among Canadians With Stroke Between 1996 and 2005
Is Health-Related Quality of Life Improving After Stroke? A Comparison of Health Utilities Indices Among Canadians With Stroke Between 1996 and 2005
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DOI：
10.1161/strokeaha.109.576678
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发表时间：
2010-05-01
期刊：
影响因子：
8.3
通讯作者：
Levy, Adrian R.
中科院分区：
文献类型：
--
作者：
Edwards, Jodi D.;Koehoorn, Mieke;Levy, Adrian R.
背景和目的：最近在诊断、治疗和康复方面的创新已经使急性卒中后的临床和功能结局得到了可测量的改善。然而，中风后健康相关生活质量的改善是否也发生了，还没有得到很好的表征。使用2加拿大人口调查，本研究的目的是确定在1996年至2005.Methods-Data从公共使用文件的全国人口健康调查，周期2（1996年），和加拿大社区健康调查，周期3.1个人中风的健康相关的生活质量的变化。（2005），使用。共纳入847名中风患者。使用基于健康效用指数Mark 3的自我报告的健康状况信息来生成单属性和总体健康相关生活质量评分。协方差分析和多元Logistic回归分析被用来确定调查年和中风后损害调整人口统计学变量和临床comorbidity.Results-A统计学显着和临床上重要的减少平均整体健康效用指数马克3得分的受访者与中风从1996年至2005年。此外，8个单属性健康公用事业指数Mark 3领域中有2个在调查年份之间出现了显着变化。显着更多的个人与中风报告的灵巧性和认知功能障碍，在2005年与1996年的受访者相比，这表明降低健康相关的生活质量为这些domains. Conclusion，尽管医疗管理的改善，生活质量没有改善中风后，在加拿大人口。这些发现有助于产生关于卒中后生活质量管理进展的影响的假设，并确定可能从卒中人群未来研究中受益的特定领域。（中风。2010;41：996-1000）。
Background and Purpose-Recent innovations in diagnosis, management, and rehabilitation have resulted in measurable improvements in clinical and functional outcomes after acute stroke. However, whether gains in health-related quality of life after stroke have also occurred is not well characterized. Using 2 Canadian population surveys, the purpose of this study was to identify changes in health-related quality of life in individuals with stroke from 1996 to 2005.Methods-Data from the public use files of the National Population Health Survey, Cycle 2 (1996), and the Canadian Community Health Survey, Cycle 3.1. (2005), were used. A total of 847 individuals with stroke were included. Self-reported information on health status based on the Health Utilities Index Mark 3 was used to generate single-attribute and overall health-related quality of life scores. Analysis of covariance and multiple logistic regression were used to determine the relationship between survey year and poststroke impairment adjusting for demographic variables and clinical comorbidities.Results-A statistically significant and clinically important reduction in mean overall Health Utilities Index Mark 3 scores was observed for respondents with stroke from 1996 to 2005. In addition, 2 of the 8 single-attribute Health Utilities Index Mark 3 domains showed a significant change between survey years. Significantly more individuals with stroke reported dexterity and cognitive impairment in 2005 compared with respondents in 1996, indicating reduced health-related quality of life for these domains.Conclusion-Despite improvements in medical management, quality of life is not improving after stroke in the Canadian population. These findings are useful to generate hypotheses about the impact of advances in management on quality of life after stroke and identify specific domains that may benefit from future study in stroke populations. (Stroke. 2010;41:996-1000.)