The prevalence of atopic dermatitis in Oregon schoolchildren
The prevalence of atopic dermatitis in Oregon schoolchildren
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DOI：
10.1067/mjd.2000.107773
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发表时间：
2000-10-01
影响因子：
13.8
通讯作者：
Hanifin, JM
中科院分区：
文献类型：
--
作者：
Laughter, D;Istvan, JA;Hanifin, JM
背景资料：虽然世界许多地区的调查显示，在过去的40年里，学龄儿童中特应性皮炎（AD）的患病率大大增加，但目前还没有来自美国的患病率信息。目的：我们的目的是调查最近开发的欧洲问卷的实用性，以估计城市和农村俄勒冈州学龄儿童AD的患病率。来自俄勒冈州6所城市小学和2所农村小学的5- 9岁学龄儿童的父母完成了AD症状和病史的自填Schultz-Larsen问卷（SLQ）。验证评估包括比较的问卷分数与临床检查在一组年龄匹配的儿童和特定的历史组件已知与AD。结果：数据显示，患病率为17.2%，使用标准评分标准的SLQ和下限为6.8%，根据高度严格的标准，来自使用皮肤科检查的验证研究。一个简单的问题（“医生曾经说过你的孩子有湿疹吗？“）与问卷测定结果高度一致，产生了非常高的预测准确性（91.2%）。结论：这项儿童AD频率的研究表明，AD在美国的患病率很高，与最近在欧洲和日本的研究中观察到的结果相当。
Background: Although surveys from many parts of the world have shown that the prevalence of atopic dermatitis (AD) in schoolchildren has increased greatly in the past 40 years, there is no current prevalence information from the United Slates.Objective: Our objective was to investigate the utility of a recently developed European questionnaire to estimate the prevalence of AD in urban and rural Oregon schoolchildren.Methods: The self-administered Schultz-Larsen questionnaire (SLQ) of AD symptoms and history was completed by the parents of a broad socioeconomic and ethnic mix of 5- to 9-year-old schoolchildren from 6 urban and 2 rural elementary schools in Oregon. Validation assessments included comparisons of the questionnaire scores with clinical examination in a group of age-matched children and with specific history components known to correlate with AD.Results: Data showed a prevalence of 17.2% using standard scoring criteria for the SLQ and with a lower limit of 6.8% according to highly stringent criteria derived from the validation study using dermatologic examination. A single question ("Has a doctor ever said that your child has eczema?") was highly concordant with the questionnaire determination, yielding very high predictive accuracy (91.2%).Conclusion: This study of childhood AD frequency indicates a high prevalence of AD in the United States, comparable to that recently observed from studies in Europe and Japan.