The kidney as a sensor of cardiovascular risk in essential hypertension.
The kidney as a sensor of cardiovascular risk in essential hypertension.
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肾脏作为原发性高血压心血管风险的传感器。
DOI：
10.1097/01.asn.0000034496.63958.f8
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发表时间：
2002
期刊：
影响因子：
--
通讯作者：
L. Ruilope
中科院分区：
文献类型：
--
作者：
L. Ruilope
由于失控的动脉高血压造成的肾脏损害是公认的。抗高血压治疗已经非常显著地减少了高血压患者肾脏的血管损害。然而，轻度肾功能不全的患病率仍然存在于相当大比例的高血压人群中。伴随而来的是心血管风险的显著增加，这是其他心血管危险因素聚集和血压控制不足的结果。预防和保护这些患者的肾脏和心血管损害将是未来最相关的任务之一。
Renal damage as a consequence of uncontrolled arterial hypertension is well recognized. Antihypertensive therapy has come to very significantly decrease the vascular damage in the kidneys of hypertensive patients. However, prevalence of mild renal insufficiency remains present in a significant proportion of the hypertensive population. This is accompanied by a marked increase in cardiovascular risk, as a consequence of the clustering of other cardiovascular risk factors and of insufficiently controlled BP. Prevention and protection of renal and cardiovascular damage in these patients will be one of the most relevant tasks in the future.