Growth rate evolution in improved environments under Prodigal Son dynamics.

Growth rate evolution in improved environments under Prodigal Son dynamics.
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DOI:
10.1111/eva.12403
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发表时间:
2016-10
影响因子:
4.1
通讯作者:
Collins S
Collins S
中科院分区:
生物学2区
文献类型:
--
作者:
Collins S

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我使用一个基于个体的模型来研究慢性环境富集下无性种群细胞分裂速率的演变。我表明,在环境改善后的数百代中保持增长率的增加可能会受到与更快速繁殖相关的细胞损伤增加的限制。在没有进一步进化以提高损伤耐受性或降低修复成本或损伤率的情况下,环境改善并不能可靠地导致微生物繁殖率的长期增加。在这里,更快的细胞分裂速率也会增加损伤,导致对损伤的避免或修复的选择,以及随后的人口增长下降,我称之为浪子动力学,因为“快速生活”的后果迫使恢复到祖先的增长率。了解环境富集预期可持续增加细胞分裂速率的条件对于需要快速细胞分裂(例如生物燃料反应器)或寻求避免出现快速细胞分裂速率(控制生物污垢)的应用是重要的。
I use an individual‐based model to investigate the evolution of cell division rates in asexual populations under chronic environmental enrichment. I show that maintaining increased growth rates over hundreds of generations following environmental improvement can be limited by increases in cellular damage associated with more rapid reproduction. In the absence of further evolution to either increase damage tolerance or decrease the cost of repair or rate of damage, environmental improvement does not reliably lead to long‐term increases in reproductive rate in microbes. Here, more rapid cell division rates also increases damage, leading to selection for damage avoidance or repair, and a subsequent decrease in population growth, which I call Prodigal Son dynamics, because the consequences of ‘living fast’ force a return to ancestral growth rates. Understanding the conditions under which environmental enrichment is expected to sustainably increase cell division rates is important in applications that require rapid cell division (e.g. biofuel reactors) or seek to avoid the emergence of rapid cell division rates (controlling biofouling).
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