Reflexive research ethics in fetal tissue xenotransplantation research.
Reflexive research ethics in fetal tissue xenotransplantation research.
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胎儿组织异种移植研究中的反思性研究伦理。
DOI：
10.1080/08989621.2012.728910
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Brown,Phil
中科院分区：
文献类型：
--
作者：
Panikkar,Bindu;Smith,Natasha;Brown,Phil
对于人类受试者唯一参与的生物医学研究，即提供组织或器官样本，一揽子同意，即同意将组织用于研究人员希望做的任何事情，被许多人认为足以满足法律和机构审查委员会 (IRB) 的要求。或者，详细的知情同意书可以为患者或研究参与者提供有关研究主题的更全面的信息。我们在此记录了研究人员对知情同意的信念和意见，以及我们在胎儿组织异种移植研究中采用的基于讨论的反思性研究伦理流程，以了解环境暴露对胎儿发育的影响。反思性研究伦理需要根据对可能有益或有害的相关和反思性理解来不断调整研究实践。这种反身性不仅仅是个人的努力，而是研究过程中所有参与者之间的集体关系。
For biomedical research in which the only involvement of the human subject is the provision of tissue or organ samples, a blanket consent, i.e., consent to use the tissue for anything researchers wish to do, is considered by many to be adequate for legal and Institutional Review Board (IRB) requirements. Alternatively, a detailed informed consent provides patients or study participants with more thorough information about the research topic. We document here the beliefs and opinions of the research staff on informed consent and the discussion-based reflexive research ethics process that we employed in our fetal tissue xenotransplantion research on the impact of environmental exposures on fetal development. Reflexive research ethics entails the continued adjustment of research practice according to relational and reflexive understandings of what might be beneficent or harmful. Such reflexivity is not solely an individual endeavor, but rather a collective relationship between all actors in the research process.