CHOICE OF CANCER-THERAPY VARIES WITH AGE OF PATIENT

CHOICE OF CANCER-THERAPY VARIES WITH AGE OF PATIENT
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DOI:
10.1001/jama.255.24.3385
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发表时间:
1986-06-27
影响因子:
120.7
通讯作者:
GOODWIN, JS
GOODWIN, JS
中科院分区:
医学1区
文献类型:
--
作者:
SAMET, J;HUNT, WC;GOODWIN, JS

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我们使用了新墨西哥州[美国]肿瘤登记处收集的22,899例癌症病例的数据,以检查患者年龄与选定部位癌症和急性白血病的潜在治愈性治疗之间的关系。对于大多数部位的癌症,无论是局部还是区域阶段,接受潜在治愈性治疗的病例比例随着年龄的增长而下降。对于局部阶段的癌症,未给予任何治疗的比例随着年龄的增长而增加。在确诊后的第一年内,未接受治疗的局部期病例的总死亡率远高于接受治疗的病例。这些数据表明,癌症治疗随年龄而变化,并表明有关治疗的决策受到其他疾病的影响。
We used data on 22,899 cancer cases collected by the New Mexico [USA] Tumor Registry to examine the relationship between patient age and the use of potentially curative therapy for cancers of selected sites and acute leukemias. For cancers of most sites, either local or regional stage, the proportion of cases receiving potentially curative therapy declined with age. For local-stage cancers, the proportion not given any treatment increased with age. Overall mortality rates during the first year after diagnosis were much higher for local-stage cases without treatment than for those who received treatment. These data show that cancer therapy varies with age and suggest that decision making regarding therapy is influenced by the presence of other diseases.