Genes and genotypes affecting the teeth of the mouse.
Genes and genotypes affecting the teeth of the mouse.
复制标题
影响小鼠牙齿的基因和基因型。
DOI：
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发表时间：
1965
期刊：
影响因子：
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通讯作者：
H. Grüneberg
中科院分区：
文献类型：
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作者：
H. Grüneberg
古生物学家和分类学家都对哺乳动物的牙齿进行了非常详细的研究，他们对物种之间的差异或最终在自然界中遗传的更高系统类别感兴趣。相比之下，人们对牙列的种内遗传变异性知之甚少。邀请参加由美国牙医学会赞助的“牙科高级教育研究所”，提供了一个在实验室和目前在野生家鼠中探索情况的机会。本文给出了这一研究的主要结果。发现的种内差异的程度可能有助于系统学家评估对他们所遇到的差异的重视程度；它将表明，在有限的样本中，人们在什么是“正常”的问题上很容易被误导。将要描述的两种典型的牙科综合征对牙科病理学提出了新的问题。
The teeth of mammals have been studied in great detail both by palaeontologists and by taxonomists who are interested in differences between species or higher systematic categories which are ultimately genetic in nature. By contrast, little is known about intra-specific genetic variability of the dentition. An invitation to participate in an ‘Institute for Advanced Education in Dental Research’ sponsored by the American College of Dentists provided an occasion to explore the situation in the laboratory and, presently, in the wild house mouse. The main results of this search are given in this paper. The extent of the intra-specific variance discovered may help systematists in assessing how much importance to attach to the differences they encounter; and it will be shown how easily one can be misled, in a limited sample, as to what is ‘normal’. Two characteristic dental syndromes to be described pose a new kind of problem to dental pathology.