Amplified Magnetic Resonance Imaging (aMRI)
Amplified Magnetic Resonance Imaging (aMRI)
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DOI：
10.1002/mrm.26142
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发表时间：
2016-06-01
影响因子：
3.3
通讯作者：
Moseley, Michael E.
中科院分区：
文献类型：
--
作者：
Holdsworth, Samantha J.;Rahimi, Mahdi Salmani;Moseley, Michael E.
目的：这项工作描述了一种名为放大MRI（aMRI）的新方法，该方法使用欧拉视频放大来放大心脏门控脑MRI扫描中的细微空间变化，从而更好地可视化大脑运动。aMRI方法将回顾性心脏门控电影MRI数据作为输入，应用空间分解，然后在合成运动放大电影数据集之前对MRI心脏门控帧进行时间滤波和频率选择性放大。这种方法揭示了由于心脏搏动引起的脑实质变形和动脉移位，特别是在脑干、小脑和脊髓中。aMRI具有广泛的神经和非神经临床应用的潜力，因为它可以放大和表征小的，通常几乎不可察觉的运动，并且可以使用心跳作为内源性机械驱动器来可视化组织的生物力学响应。(C)2016 Wiley Periodicals，Inc.
Purpose: This work describes a new method called amplified MRI (aMRI), which uses Eulerian video magnification to amplify the subtle spatial variations in cardiac-gated brain MRI scans and enables better visualization of brain motion.Methods: The aMRI method takes retrospective cardiac-gated cine MRI data as input, applies a spatial decomposition, followed by temporal filtering and frequency-selective amplification of the MRI cardiac-gated frames before synthesizing a motion-amplified cine data set.Results: This approach reveals deformations of the brain parenchyma and displacements of arteries due to cardiac pulsatility, especially in the brainstem, cerebellum, and spinal cord.Conclusion: aMRI has the potential for widespread neuro- and non-neuro clinical use because it can amplify and characterize small, often barely perceptible motion and can visualize the biomechanical response of tissues using the heartbeat as an endogenous mechanical driver. (C) 2016 Wiley Periodicals, Inc.