Synthesis of (Arylal kenyl)si lanes by palladium-catalyzed regiospecific and stereoselective allyl transfer from silyl-substituted homoallyl alcohols to aryl halides
Synthesis of (Arylal kenyl)si lanes by palladium-catalyzed regiospecific and stereoselective allyl transfer from silyl-substituted homoallyl alcohols to aryl halides
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DOI：
10.1021/ja0755111
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发表时间：
2007-10-24
影响因子：
15
通讯作者：
Oshima, Koichiro
中科院分区：
文献类型：
--
作者：
Hayashi, Sayuri;Hirano, Koji;Oshima, Koichiro
在钯的催化下，硅基取代的高烯丙醇与芳基卤化物发生区域选择性和立体选择性的烯丙基转移，生成(E)-3-芳基-1-烯基-、(E)-1-芳基-2-烯基和旋光活性的(E)-L-芳基-2-丁烯基硅烷。
The reactions of silyl-substituted homoallyl alcohols with aryl halides under palladium catalysis result in regiospecific and stereoselective allyl transfer from the alcohols to aryl halides, offering modular synthesis of (E)-3-aryl-1-alkenyl-, (E)-1-aryl-2-alkenyl-, and optically active (E)-l-aryl-2-butenylsilanes.