MICROTUBULE STRUCTURE AT LOW RESOLUTION BY X-RAY-DIFFRACTION

MICROTUBULE STRUCTURE AT LOW RESOLUTION BY X-RAY-DIFFRACTION
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DOI:
10.1073/pnas.74.8.3370
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发表时间:
1977-01-01
影响因子:
11.1
通讯作者:
COHEN, C
COHEN, C
中科院分区:
综合性期刊1区
文献类型:
--
作者:
MANDELKOW, E;THOMAS, J;COHEN, C

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取向的水合[小牛脑]细胞质微管的X射线图的分析表明,微管壁从约70-150埃延伸。放射状的壁的中心区域看起来是均匀的,但外表面被垂直的凹槽分开13个原丝和一个陡峭的10倍的凹槽家族细分。内表面主要是10头沟,原丝之间没有明显的细分。
Analysis of X-ray diagrams of oriented hydrated [calf brain] cytoplasmic microtubules shows that the tubule wall extends from about 70-150 .ANG. radially. The central region of the wall appears homogeneous, but the outside surface is subdivided by vertical grooves separating the 13 protofilaments and by a steep 10-fold family of grooves. The inside surface is dominated by the 10-start grooves with no clear subdivision between the protofilaments.