Callynormine A, a new marine cyclic peptide of a novel class
Callynormine A, a new marine cyclic peptide of a novel class
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DOI：
10.1021/ol0491787
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发表时间：
2004-07-22
期刊：
影响因子：
5.2
通讯作者：
Kashman, Y
中科院分区：
文献类型：
--
作者：
Berer, N;Rudi, A;Kashman, Y
从肯尼亚海绵异形海绵中分离得到一种新的环肽，其结构经核磁共振数据解析和X-射线衍射法确证。卡利诺明A代表了一类新的具有α-氨基-β-氨基丙烯酰胺环化功能的杂合环肽(指定为烯二氨基)。
A novel cyclic peptide, callynormine A, was isolated from the Kenyan marine sponge Callyspongia abnormis and its structure elucidated by interpretation of its NMR data and X-ray diffraction analysis. Callynormine A represents a new class of heterodetic cyclic peptides (designated endiamino peptides) possessing an alpha-amido-beta-aminoacrylamide cyclization functionality.