Case-by-case assessment of adult-onset asthma attributable to occupational exposures among members of a health maintenance organization.
Case-by-case assessment of adult-onset asthma attributable to occupational exposures among members of a health maintenance organization.
复制标题
对健康维护组织成员中因职业暴露导致的成人哮喘的逐案评估。
DOI：
10.1097/01.jom.0000199437.33100.cf
复制
发表时间：
2006
影响因子：
3.2
通讯作者：
Rosiello,RichardA
中科院分区：
文献类型：
--
作者：
Sama,SusanR;Milton,DonaldK;Hunt,PhillipR;Houseman,EAndres;Henneberger,PaulK;Rosiello,RichardA
目的：在有健康保险的一般就业人群中，由职业暴露引起的成人发病哮喘的比例是多少？方法：我们进行了一项为期 2 年的前瞻性研究，以确定健康维护组织 (HMO) 成员中成人发病的哮喘。通过电话访谈了解职业暴露、症状、药物使用和触发因素，以评估每个病例患工作相关哮喘的可能性。使用加权估计方程根据与访谈参与相关的因素来调整可归因于工作场所暴露的哮喘比例。结果：总体而言，29%（95%置信区间，25-34%）的成人发病哮喘可归因于工作场所暴露；分别有 26%（21-30%）和 22%（18-27%）的病例因职业刺激物和致敏剂暴露而患有哮喘。结论：职业暴露（包括刺激物）是成人发病哮喘的重要原因。相对较少的社区研究对因职业接触而引起的病例比例（职业归因比例）进行了总体衡量。曝光。 1-6 这项研究前瞻性地确定了马萨诸塞州中部一家健康维护组织 (HMO) 成年成员中的成人哮喘病例。本文中的分析旨在根据专家暴露评分、工作相关症状和哮喘药物使用来衡量可能患有工作相关哮喘的病例比例。根据职业性哮喘的医生病例报告，与工作相关的哮喘比例估计为 1% 至 6%，而基于社区的哮喘风险研究则高达 36%。 4, 7, 8 很少有研究报告美国哮喘的职业归因比例。 9
Objective:In a general population of employed persons with health insurance, what proportion of adult-onset asthma is caused by occupational exposures?Method:We conducted a 2-year prospective study to identify adult-onset asthma among health maintenance organization (HMO) members. Telephone interviews regarding occupational exposures, symptoms, medication use, and triggers were used to assess likelihood of work-related asthma for each case. Weighted estimating equations were used to adjust the proportion of asthma attributable to workplace exposures for factors associated with interview participation.Results:Overall, 29%(95% confidence interval, 25–34%) of adult-onset asthma was attributable to workplace exposures; 26%(21–30%) and 22%(18–27%) of cases had asthma attributable to occupational irritant and sensitizer exposures, respectively.Conclusions:Occupational exposures, including irritants, are important causes of adult-onset asthma.Relatively few community-based studies have been conducted to provide an overall measure of the fraction (occupational attributable fraction) of cases that arise as a result of occupational exposures. 1–6 This study prospectively identified adult-onset asthma cases in the adult members of a health maintenance organization (HMO) based in central Massachusetts. The analyses in this article were designed to measure the proportion of cases that were likely to have work-related asthma based on expert exposure scores and work-related symptoms and asthma medication use. Estimates of the proportion of asthma that is work-related range from 1% to 6% based on physician case reports of occupational asthma up to 36% in community-based studies of asthma risk. 4, 7, 8 Few studies have reported on the occupational-attributable fraction of asthma in the United States. 9
伯爵：有感觉：认知、社会和情感维度
DOI：
--
发表时间：
1978
期刊：
--
影响因子：
--
作者：
P. Cowan
通讯作者：
P. Cowan
道德发展和行为：理论、研究和社会问题
DOI：
10.2307/582353
发表时间：
1976
期刊：
The Family Coordinator
影响因子：
--
作者：
L. Henley;T. Lickona
通讯作者：
T. Lickona
社会化与社会
影响因子：
9.1
作者：
J. Moore;J. Clausen
通讯作者：
J. Clausen