Clinical importance of impedance measurements
Clinical importance of impedance measurements
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DOI：
10.1097/mcg.0b013e31815f8e17
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发表时间：
2008-05-01
影响因子：
2.9
通讯作者：
Castell, Donald O.
中科院分区：
文献类型：
--
作者：
Agrawal, Amit;Castell, Donald O.
背景：由于阻抗变化被证明是检测食道内液体或气体运动的敏感和可靠的手段，世界各地的许多研究都探讨了阻抗测定的可能性，以提供对食道运输功能或胃食道反流的存在和程度的灵敏测量。目的：回顾阻抗测量的临床重要性。结论：动态MII-pH监测是一种有价值的评估反流的工具，因为它不仅能识别酸反流，而且能显示所有反流类型，包括酸和非酸，从而克服了简单pH监测的不足。我们相信，质子泵抑制剂治疗的MII-pH测试已经成为检测反流和澄清其与症状的关系的新的“金标准”。
Background: Because impedance changes have been shown to be a sensitive and reliable means to detect fluid or gas movement within the esophagus, numerous studies worldwide have addressed the potential for impedance determinations to provide a sensitive measure of either esophageal transit function or the presence and extent of gastroesophageal reflux. Using a catheter with multiple impedance measuring sites [multichannel intraluminal impedance (MII)] allows the opportunity to track fluid movement within the esophagus.Aim: To review the clinical importance of impedance measurements.Conclusions: Ambulatory MII-pH monitoring is a valuable tool in the assessment of reflux because it identifies not only acid reflux but overcomes the deficiency of simple pH monitoring by showing all reflux types, both acid and nonacid. It is our belief that MII-pH testing on proton pump inhibitor therapy has become the new "gold standard" for detection of reflux and for clarifying its relationship to symptoms.