Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients.
Computational fluid dynamics simulation of the upper airway response to large incisor retraction in adult class I bimaxillary protrusion patients.
复制标题
成人 I 类双颌前突患者上气道对大切牙后缩反应的计算流体动力学模拟
DOI：
10.1038/srep45706
复制
发表时间：
2017-04-07
影响因子：
4.6
通讯作者：
Liu D
中科院分区：
文献类型：
--
作者：
Zheng Z;Liu H;Xu Q;Wu W;Du L;Chen H;Zhang Y;Liu D
成人安氏I类双颌前突患者切牙大范围内收后上气道的变化主要集中在解剖变化上，而忽略了功能变化。本研究旨在利用基于计算流体动力学（CFD）的功能图像研究成人安氏I类双颌前突患者拔牙矫治后上气道的变化。根据30例完成拔牙治疗的患者的CBCT进行三维重建后，进行CFD。治疗后，最小区、口咽部和下咽部的压降显著增加。治疗前最小压力和最大流速主要位于下咽部，治疗后主要位于口咽部。结果显示，压力降与解剖参数、治疗效果之间存在显著相关性，而压力降与鼻咽部容积之间无显著相关性，提示成人双颌前突患者在最大支抗拔牙矫治后，咽部塌陷的风险增加。在临床治疗中应考虑这些不良变化，尤其是对高危患者，以避免不必要的呼吸功能减弱。
The changes of the upper airway after large retraction of the incisors in adult class I bimaxillary protrusion patients were assessed mainly focused on the anatomic variation and ignored the functional changes. This study aimed to investigate the changes of the upper airway in adult class I bimaxillary protrusion patients after extraction treatment using the functional images based on computational fluid dynamics (CFD). CFD was implemented after 3D reconstruction based on the CBCT of 30 patients who have completed extraction treatment. After treatment, pressure drop in the minimum area, oropharynx, and hypopharynx increased significantly. The minimum pressure and the maximum velocity mainly located in the hypopharynx in pre-treatment while they mostly occured in the oropharynx after treatment. Statistically significant correlation between pressure drop and anatomic parameters, pressure drop and treatment outcomes was found. No statistical significance changes in pressure drop and volume of nasopharynx was found. This study suggested that the risk of pharyngeal collapsing become higher after extraction treatment with maximum anchorage in bimaxillary protrusion adult patients. Those adverse changes should be taken into consideration especially for high-risk patients to avoid undesired weakening of the respiratory function in clinical treatment.