Validation of simplified PESI score for identification of low-risk patients with pulmonary embolism: From the COMMAND VTE Registry
Validation of simplified PESI score for identification of low-risk patients with pulmonary embolism: From the COMMAND VTE Registry
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DOI：
10.1177/2048872618799993
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发表时间：
2020-06-01
影响因子：
4.1
通讯作者：
Kimura, Takeshi
中科院分区：
文献类型：
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作者：
Yamashita, Yugo;Morimoto, Takeshi;Kimura, Takeshi
背景资料：据报道，简化肺栓塞严重程度指数（sPESI）评分可用于预测肺栓塞患者的30天死亡率，有助于识别低风险患者，以便早期出院或在家治疗。然而，治疗决策也应该基于其他mortality.Methods的不良事件的风险：COMMAND静脉血栓栓塞登记是一个多中心的注册登记连续患者急性症状性静脉血栓栓塞在日本2010年1月至2014年8月，目前的研究人群包括1715例肺栓塞。我们计算每个患者的sPESI评分，并比较30天的死亡率，复发性静脉血栓栓塞和大出血之间的sPESI评分为0和1或greater.Results：与sPESI评分为0的患者占383（22%）的患者，和110（6.4%）的患者在30天内死亡。sPESI评分为0的患者的累积30天死亡率低于sPESI评分为1或更高的患者（0.5% vs. 8.1%，对数秩P
Background: The simplified pulmonary embolism severity index (sPESI) score has been reported to be useful in predicting 30-day mortality for patients with pulmonary embolism, which helps the identification of low-risk patients for early hospital discharge or home treatment. However, therapeutic decision-making should also be based on the risks of adverse events other than mortality.Methods: The COMMAND VTE Registry is a multicentre registry enrolling consecutive patients with acute symptomatic venous thromboembolism in Japan between January 2010 and August 2014, and the current study population consisted of 1715 patients with pulmonary embolism. We calculated the sPESI score for each patient, and compared 30-day rates of mortality, recurrent venous thromboembolism and major bleeding between sPESI scores of 0 and 1 or greater.Results: Patients with a sPESI score of 0 accounted for 383 (22%) patients, and 110 (6.4%) patients died within 30 days. The cumulative 30-day incidence of mortality was lower in patients with a sPESI score of 0 than those with a sPESI score of 1 or greater (0.5% vs. 8.1%, log rank P