EBNEO Commentary: Does the effect of hydrocortisone in preterm infants depend on the baseline risk of BPD?

EBNEO Commentary: Does the effect of hydrocortisone in preterm infants depend on the baseline risk of BPD?
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EBNEO 评论:氢化可的松对早产儿的影响是否取决于 BPD 的基线风险?

DOI:
10.1111/apa.16977
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发表时间:
2023
期刊:
Acta paediatrica (Oslo, Norway : 1992)
影响因子:
--
通讯作者:
Bamat,NicolasA
Bamat,NicolasA
中科院分区:
--
文献类型:
--
作者:
Nelin,TimothyD;Bamat,NicolasA

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方法设计:对NICHD NRN氢化可的松试验(800名早产儿的双盲、安慰剂对照、随机临床试验)进行二次事后分析。参与者:早产儿出生于妊娠< 30周,在出生后14至28天之间进入研究时接受机械通气,并接受机械通气至少7天。婴儿被随机分为氢化可的松组和安慰剂组,为期10天。
MethodsDesign:Secondary post hoc analysis of the NICHD NRN Hydrocortisone Trial (double-masked, placebo-controlled, randomized clinical trial of 800 preterm infants).Participants:Preterm infants born at< 30 weeks’ gestation, receiving mechanical ventilation at study entry between 14 and 28 postnatal days, and underwent mechanical ventilation for at least 7 days. Infants were randomized to either hydrocortisone or placebo treatment over a 10-day course.
DOI: 10.1016/s0140-6736(16)00202-6
发表时间: 2016-04-30
期刊: LANCET
影响因子: 168.9
作者:
Baud, Olivier;Maury, Laure;Alberti, Corinne
通讯作者: Alberti, Corinne