Nationwide seroepidemiology of hepatitis B virus infection in South Korea in 2009 emphasizes the coexistence of HBsAg and anti-HBs

Nationwide seroepidemiology of hepatitis B virus infection in South Korea in 2009 emphasizes the coexistence of HBsAg and anti-HBs
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DOI:
10.1002/jmv.23594
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发表时间:
2013-08-01
影响因子:
12.7
通讯作者:
Ki, Moran
Ki, Moran
中科院分区:
医学3区
文献类型:
--
作者:
Lee, Byung Seok;Cho, Yong Kyun;Ki, Moran

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乙型肝炎病毒(HBV)感染是韩国慢性肝病的主要原因。本研究调查了乙型肝炎病毒感染的血清阳性率,重点研究了乙型肝炎表面抗原(HBsAg)和抗体(anti-HBs)的共存情况。2009年,总共招募了290 212人在29个机构接受健康检查。使用2009年韩国估计人口,根据年龄、性别和地理区域调整HBsAg和anti-HBs的粗血清患病率。调整后血清HBsAg和anti-HBs阳性率分别为4.0%和73.5%。男性HBsAg阳性高于女性,anti-HBs阳性低于女性(P
Hepatitis B virus (HBV) infection is the major cause of chronic liver disease in Korea. This study investigated the seroprevalence of HBV infection with an emphasis on the coexistence of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs). In all, 290,212 people undergoing health check-up examinations in 29 institutions during 2009 were recruited. The crude seroprevalences of HBsAg and anti-HBs was adjusted by age, sex, and geographic area using the 2009 estimated population of Korea. The adjusted seroprevalences of HBsAg and anti-HBs was 4.0% and 73.5%, respectively. Males showed higher HBsAg positivity and lower anti-HBs positivity than females (P