A Computational Fluid Dynamics Study Pre- and Post-Stent Graft Placement in an Acute Type B Aortic Dissection
A Computational Fluid Dynamics Study Pre- and Post-Stent Graft Placement in an Acute Type B Aortic Dissection
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DOI：
10.1177/1538574410389342
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发表时间：
2011-02-01
影响因子：
0.9
通讯作者：
Lumsden, Alan B.
中科院分区：
文献类型：
--
作者：
Karmonik, Christof;Bismuth, Jean;Lumsden, Alan B.
目的：展示计算流体动力学 (CFD) 量化 B 型主动脉夹层 (TB-AD) 治疗前/治疗后血流动力学的能力。方法：根据动态磁共振图像数据初始化的 CFD 模拟，对血管内治疗后的壁剪切应力 (WSS) 和动态压力 (dynP) 变化进行量化。结果：经过一年的随访，胸主动脉段完全重塑，腹主动脉中出现持续的、无血栓的假腔。治疗前，入口撕裂处出现较大的 VVSS (> 5 Pa) 和 dynP (> 80 Pa)，并且真腔 (TL) 内出现狭窄区域。治疗后，除覆膜支架近端和再入撕裂处外，TL 中的 WSS 低于 3.3 Pa，dynP 低于 55 Pa。覆膜支架内存在两个高 dynP 焦点位置。结论：计算流体动力学可以对 TB-AD 中的血流动力学壁力进行定量评估，这可能对后续检查感兴趣。
Purpose: To demonstrate the capability of computational fluid dynamics (CFD) for quantifying hemodynamic forces pretreatment/posttreatment in type B aortic dissection (TB-AD). Methods: From CFD simulations initialized with dynamic magnetic resonance image data, wall shear stress (WSS) and dynamic pressure (dynP) changes post endovascular treatment were quantified. Results: After I year follow-up, thoracic aortic segment was completely remodeled, and persistent, nonthrombosed false lumen in the abdominal aorta was noted. Pretreatment, large VVSS (> 5 Pa) and dynP (> 80 Pa) occurred at entrance tear and a stenotic region in the true lumen (TL). Posttreatment, WSS was lower than 3.3 Pa and dynP was lower than 55 Pa in TL, except at proximal end of the stent graft and at reentrance tear. Two focal locations of high dynP existed within the stent graft. Conclusions: Computational fluid dynamics may provide quantitative assessment of hemodynamic wall forces in TB-AD potentially of interest for follow-up examinations.